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Biomedical subjects

B Jonsson

Publications and source records attributed to B Jonsson.

At least 109 records · Page 6Linked to original sources

Functional improvement and costs of hip and knee arthroplasty in destructive rheumatoid arthritis.

Functional improvement and costs were analysed in 54 patients after 23 hip and 31 knee arthroplasties. All patients had destructive RA (ARA criteria 5-8). Mean stay at the surgical department was 15 and 26 days respectively, regardless of preoperative locomotion status, sex, or age, but additional in-patient rehabilitation was significantly longer after knee than hip arthroplasty (11 days and 4 days, respectively). Subjective and objective status as evaluated with total locomotion score showed significant improvement 6 months after operation. The degree of over-all improvement was equal for men and women, for all age groups, and for the different score groups. Quality of life improved with pain relief, improved sleep, and improved walking ability. The mean total costs were 34,902 SEK for hip and 56,200 SEK for knee replacement, including in-patient rehabilitation. Costs for home help were reduced from 693,600 SEK to 479,400 SEK. Severely disabled patients showed satisfactory improvement, but did not reach the functional level achieved by patients who were less disabled at the time of operation. Costs were not significantly higher for the former category.

Adult↗

Rheumatoid arthritis evaluated by locomotion score. A population study.

The effects of rheumatoid arthritis on locomotion status were assessed in an epidemiologically representative Swedish population sample. In a steady community of 12,707 inhabitants, 82 patients were found fulfilling ARA criteria 5-8 (Rome 1961). Prevalence was 0.51% for men, 0.78 for women and 0.65 in the overall population (unpublished observation). The ratio women:men was 1:0.67. Mean age was 65 (30-92) years, age at onset 47 (7-91) and disease duration 19 (1-65) years. All patients were evaluated clinically with total locomotion score (best = 100, worst = 0). This was 72 (24-96) overall; 76 (24-96) for men and 68 (30-94) for women. Among the ages above 64, women had significantly (p less than 0.02) lower scores than men. Mean subjective score (max. 100) was 62 (4-93) overall; 67 (5-93) for men and 58 (9-92) for women, and objective score (max. 100) 82 (23-100); 85 (44-99) for men and 78 (23-100) for women. Over the years, a total of 108 reconstructive operations had been performed on 36 out of the 82 patients (44%). Indication for further reconstructive surgery was found in as many as 56% of the patients, including 58 major joint replacements. Scores for patients in need of operation were significantly lower than those for those who were considered not to need an operation.

Adult↗

Hand function and total locomotion status in rheumatoid arthritis. An epidemiologic study.

The effects of destructive rheumatoid arthritis (RA) on hand function, as well as total locomotion status, were assessed in a Swedish population sample. In a community of 12,707 inhabitants, 82 were found with RA fulfilling ARA criteria 5-8, i.e., a prevalence of 0.7 percent. Seventy-seven of the 82 cases were evaluated with Sollerman's hand function test and our total locomotion score. The mean hand score (max. 80) was 61 (0-78), with no difference between the right and the left hand or between men and women. Hand function worsened with increasing age of the patient, as well as with increasing disease duration. It was highly correlated with the total locomotion status of the patient. A high correlation was found between hand function and hospital care. However, total medical or social costs for these patients were not related to hand function, but merely to the status of the lower extremities.

Adult↗

Elbow arthroplasty in rheumatoid arthritis. Function after 1-2 years in 20 cases.

The function of the hand and arm was studied after total elbow arthroplasty in a consecutive series of 18 rheumatoid patients with a total of 20 primary arthroplasties and one revision. Extensive clinical evaluation with locomotion score and Sollerman's hand function test was undertaken preoperatively and at 6 months postoperatively. The mean flexion range increased 25 degrees and extension lag decreased 5 degrees. Pain relief was achieved in all the cases, and 16 of 20 primary operated on elbows became fully painfree. Hand function score (max. 80) improved from 52 to 64, upper extremity score (max. 100) from 57 to 68 and subjective score (max. 100) from 46 to 58. Complications were 2 cases of ulnar nerve paresthesia and 1 epicondylar fissure.

Adult↗

Repeated mid-cycle tests of in-vitro sperm penetration (Kremer tests) in healthy women during three menstrual cycles.

The outcome of Kremer testing has been evaluated daily, during the mid-cycle, in 15 healthy women over three menstrual cycles, using a permanent and a variable normal, male donor. There was a significant correlation (r = 0.539; t = 6.33; P less than 0.001, n = 100; Spearman rank correlation with correction for ties) between the results obtained with the two men. The best Kremer test results were seen on the day of the LH peak and the two preceding days. No correlation was present between serum oestradiol levels and Kremer test results except on the day before the LH surge. Enough cervical mucus for Kremer testing was obtained when serum oestradiol levels were a mean of 693 pmol/l (range 214-2140). Variations in Kremer test results obtained in one woman's menstrual cycle were of the same magnitude as the difference between women. Four women had a favourable mid-cycle Kremer test result in all three cycles studied, six women had a favourable mid-cycle Kremer test result during two of their three cycles and five women only during one of the three cycles studied. The outcome of the Kremer test was not directly correlated to the quality of the cervical mucus as evaluated by the scoring system used by WHO. It is suggested that the Kremer test, performed with two male donors daily during the mid-cycle in three menstrual cycles, affords results that will allow reliable prediction of conceptional potential.

Adult↗

Locomotion score in rheumatoid arthritis.

A total locomotion score suited for clinical evaluation of patients with rheumatoid arthritis was developed and fulfilled the 1980 criteria of WHO. The grading system distinguished a subjective score for pain and ability from an objective score for physical signs, and it assessed the upper and lower extremities separately. The total locomotion score consisted of the total subjective and total objective scores combined. The three total assessments each showed a linear relationship to Steinbrocker's four functional classes when tested in 106 rheumatoid patients with ARA criteria 5-8. The interobserver reliability was good. The multifactorial assessment data were monitored by a computer.

Activities of Daily Living↗

The static load component in muscle work.

By citing examples from actual work situations and discussing the concept of muscular endurance and fatigue this paper is intended to provide an account of past and current research on the "static" component of muscular load during work. By amplitude probability distribution analysis of electromyographic signals it is possible to estimate the "static level" of muscular load during work. Electromyographic studies of job rotation between different assembly tasks in electronic industries often show that there are quantitatively and qualitatively only small differences in muscular load between different tasks.

Biomechanical Phenomena↗

Intraarticular pressure during operation of cervical hip fractures.

The intraarticular pressure was measured during nailing of femoral neck fractures in 21 patients. A three-flanged nail or three screws were used randomly. During traction and inward rotation of the leg, the intracapsular pressure increased over diastolic values, but as soon as the lateral cortex was penetrated, the pressure dropped. The hammering of the nail did not increase the intraarticular pressure.

Adult↗

Alignment and long-term clinical results of a semiconstrained knee prosthesis.

In knee arthroplasty, component malpositioning seems to be a fundamental cause for failure. The degree of malpositioning is important. To investigate this degree, 86 of 137 knee arthroplasties performed with the Townley semiconstrained bicondylar prosthesis were examined after a mean follow-up period of 6.5 years (range, 5.0-8.5 years). Five arthroplasties were excluded because of aseptic loosening, but none of these showed malalignment in postoperative roentgenograms. Clinical results and the patients' reports on deterioration of prosthetic function were correlated with positioning of the prosthetic components. Total alignment between 6 degrees of varus and 7 degrees of valgus was associated with good clinical results. Total alignment of more than 7 degrees of valgus, anterior tilting of the tibial component, or positioning of the femoral component in more than 12 degrees of valgus correlated with relatively poor clinical results.

Adult↗

The importance of variations in questionnaire administration.

A standardised Nordic questionnaire for the analysis of musculoskeletal symptoms was administered to Swedish bus drivers and shunters in two different ways. The first was a cohort study in which all questions were focused on musculoskeletal troubles, whilst the other was the administration of the standardised questionnaire during a general health examination. Higher frequencies of musculoskeletal troubles were reported in the cohort study. When this type of questionnaire was administered prior to the general health examination, no differences were seen, which may be an effect of focusing first on the musculoskeletal symptoms. It can thus be concluded that it is important, not only to use standardised questionnaires, but also to consider the way the questionnaire is administered when comparing the results from different studies.

Journal Article↗

Standardised Nordic questionnaires for the analysis of musculoskeletal symptoms.

Standardised questionnaires for the analysis of musculoskeletal symptoms in an ergonomic or occupational health context are presented. The questions are forced choice variants and may be either self-administered or used in interviews. They concentrate on symptoms most often encountered in an occupational setting. The reliability of the questionnaires has been shown to be acceptable. Specific characteristics of work strain are reflected in the frequency of responses to the questionnaires.

Journal Article↗

New attachment in monkeys with experimental periodontitis with and without removal of the cementum.

Experimental periodontitis was induced in monkeys by means of elastic orthodontic ligatures. The periodontally-involved teeth were then treated with different methods. At the end of the treatment period, the monkeys were sacrificed. The premolar-molar areas were dissected out and embedded in a low-viscosity embedding medium (Spurr). The results of the treatment procedures were analyzed on ground sections. Formation of new cementum and new bone was determined by means of tetracycline labeling. Root planing with an ultrasonic device or with hand instruments almost completely removed the cementum and a portion of the peripheral dentin. The root surface was more uneven after treatment with the ultrasonic device than after using hand instruments. No new attachment could be found after root planing. Cleaning of the periodontally-involved root surfaces with two detergents (cetylpyrimidinium chloride and sodium-N-lauroyl sarcosine) without root planing resulted in a significant amount of new attachment.

Animals↗

Mean power frequency and integrated electromyogram of repeated isokinetic plantar flexions.

Peak torque (PT), contraction work (CW), mean power (CP), and time for contraction (t) were recorded for each of 200 full range-of-motion repetitive isokinetic (maximum effort) plantar flexions at the preset angular velocity 60 degrees s-1 (degrees X s-1). The subjects were 12 healthy males (42-46 years). Simultaneous recordings of electromyographic activity of the three parts of the triceps surae muscle were made. The electromyograms were truly integrated and the mean power frequency was also calculated for each of the contractions. The mechanical variables decreased steeply during approximately the first 70 contractions (the fatigue phase) followed by a steady-state level (the endurance level) with no further significant decrease. The fatigue phase was composed of two parts. The first was characterized by decreases in CW, MPF and in the ratio CW/iEMG, while iEMG and iEMG/t were unaltered. During the second part decreases in iEMG and iEMG/t occurred while MPF and CW/iEMG had stabilized. During the endurance level all the variables were stable but lowered when compared with the initial contractions of the fatigue phase. The results indicated that the mechanical fatigue went through two parts before the steady-state level was established.

Adult↗