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Biomedical subjects

B Lundström

Publications and source records attributed to B Lundström.

At least 37 records · Page 2Linked to original sources
PubMed1984

Clinical problems in relation to breast cancer screening with mammography. A preliminary report.

In the mammography screening in Ostergötland county, a shift to more favourable stages of breast tumours has been observed after five years of screening: stage I 71% and stage II 29% in the study group compared with stage I 40% and stage II 60% in the control group. 1 429 women were referred for clinical examination. 418 (29%) turned out to have breast carcinomas. 339 patients (23%) needed more than one clinical examination for definite diagnosis. 49% of the tumours were smaller than 11 mm, and only 32% of the small invasive cancers were suspected of malignancy at the clinical examination.

Adult↗
PubMed1983

Assessment of deep venous insufficiency by ascending phlebography.

Retrograde femoral phlebography performed in the supine and erect positions are compared. In deep venous insufficiency, the contrast medium passes considerably farther down in the retrograde direction in examinations with the patient in the erect position. A comparison was made between ascending and retrograde techniques in order to find out what predictive value conventional ascending phlebography of the lower limb may have with regard to the function of the valves in the femoral vein. Layering of the contrast medium in the valvular sinus is a very reliable sign of valvular competence and was observed in two-thirds of the cases without deep venous insufficiency. This figure can be increased by a slight modification of the method of examination. Absence of layering does not necessarily indicate deep venous insufficiency.

Adult↗
PubMed1983

Idiopathic retroperitoneal fibrosis and common bile duct stenosis. A case report.

The ordinary manifestations of idiopathic retroperitoneal fibrosis (IRF) with involvement of the ureters and urinary obstruction are well known. Quite a number of publications have made it clear that this disease process can often also affect organ systems other than the urinary tract--from the trachea and mediastinum to the rectum. The present case report calls attention to the fact that IRF may also be a surgically treatable cause of obstructive icterus.

Adult↗
PubMed1981

Cross-cultural approaches to transsexualism. A comparison between Sweden and Australia.

Several hypotheses with regard to the influence of societal factors including the rigidity of the society with regard to sex roles, sexual equality and homosexual behaviour were tested comparing prevalence, incidence and sex ratio of transsexualism between Sweden and Australia, two societies which differ with respect to these factors while otherwise remaining comparable as Western democratic societies of about the same size and level of technological development. Significant differences were found between the two countries in both frequency and sex ratio of transsexualism. These findings are discussed and it is concluded that societal influences seem to have an influence on the number of transsexuals presenting as patients. Further research is needed to assess whether these factors also influence aetiology and development of transsexualism.

Australia↗
PubMed1981

Human thyroid blood flow response to endogenous, exogenous human, and bovine thyrotrophin measured by electromagnetic flowmetry.

Human thyroid blood flow (TBF) was studied with electromagnetic flowmetry during operation. Measurements were made of the effect on TBF of injections of bovine TSH into one inferior thyroid artery in 6 patients; 6 other patients were given human TSH, and in 10 patients measurements were made both of TBF and endogenous TSH released after administration of TRH in a peripheral vein. The TBF increased after all three types of injection. The mean of the TBF maxima after bovine TSH was 2.26 +/- 0.35 (mean +/- SEM) relative to basal TBF, after human TSH 1.97 +/- 0.28, and after TRH 1.64 +/- 0.20. In the three groups combined it was 1.92 +/- 0.16. The TBF was often increased already during the first recording period 1-10 min after TSH or TRH administration. The mean TBF was approximately doubled at 30-50 min. There were considerable inter-individual variations in the latent time and maximum response of TBF, especially after human TSH, but we found no correlation between the response and the TSH serum concentration in any group. A prompt, but inter-individually varying, increase in TBF was confirmed. This increase is suggested to be secondary to an increased intrafollicular metabolic activity and not primarily regulating thyroid function.

Adult↗
PubMed1981

[14C]Oxalate absorption by normal persons, calcium oxalate stone formers, and patients with surgically disturbed intestinal function.

Intestinal absorption of oxalate can be judged from the urinary excretion of orally administered [14C]oxalate. Fifteen normal subjects, 21 patients with "idiopathic" calcium oxalate stone disease and a high oxalate excretion, four patients operated with ileocecal resection, and seven patients operated with jejunoileal bypass were so investigated. We saw no significant difference in the amount of isotope excreted by normal subjects and idiopathic stone formers; 13.6% (SD 5.9%) and 14.4% (SD 6.5%), respectively, of the administered dose was accounted for in the urine. The patients with resection or bypass showed a quite different pattern of isotope excretion, and 18.3% (SD 7.0%) and 36.8% (SD 14.0%), respectively, of the isotope was accounted for in the urine.

Calcium Oxalate↗
PubMed1981

Complications to subtotal parathyroidectomy.

Seventy-three patients were operated on for confirmed hyperparathyroidism. Identification of all glands was done by 1/3 biopsies for histopathologic examination on frozen section during the operation. In cases of adenoma only, the adenoma was removed except for the biopsies. In cases of hyperplasia, subtotal resection was made, leaving between a half-gland and a whole gland. The frequency of complications was analysed. Temporary hypocalcemia occurred in a similar frequency in both adenoma and hyperplasia groups. Permanent hypocalcemia was present in only one patient. At follow-up 3-5 years after operation, 98.6% of the patients were normocalcemic. Ionized and total serum calcium were normalized 3 months after operation and remained so for the rest of the follow-up period. Serum phosphate, serum magnesium and serum parathormone also remained normal. Thus identification of parathyroid glands with biopsies or subtotal parathyroidectomy in cases with hyperplasia did not increase the risk of postoperative complications.

Adult↗
PubMed1981

The importance of elevated TSH in serum after subtotal thyroidectomy for hyperthyroidism. A five-year follow-up study.

68 patients operated on for hyperthyroidism were observed regularly for 5 years after operation as regards the concentration of TSH in serum and the incidence of hypothyroidism and recurrent hyperthyroidism. 20 patients had elevated TSH 6 weeks after operation. 5 years later 9 of them had developed hypothyroidism, 6 had elevated TSH without clinical symptoms of hypothyroidism, while 5 were normal in all measured thyroid variables. 48 patients had normal TSH 6 weeks after operation. 5 years later 5 of them had developed a recurrence of hyperthyroidism, 4 had elevated TSH with no clinical symptoms of hypothyroidism, while the remaining 39 patients were euthyroid with normal thyroid variables. A scheme for follow-up of patients operated on for hyperthyroidism is proposed, with close follow-up of patients with elevated TSH soon after operation.

Adult↗
PubMed1980

Thyroid morphology and function after subtotal resection for hyperthyroidism.

Two main patterns of hyperplasia of the thyroid epithelium are seen in hyperthyroidism--toxic diffuse hyperplasia and toxic nodular hyperplasia. Toxic diffuse hyperplasia may affect the entire gland or it may arise in the extranodular tissue in a gland with nodular lesions. A series of patients treated by subtotal thyroidectomy for hyperthyroidism were classified into three morphological groups of goitre: 98 had a toxic diffuse goitre (TDG), 58 toxic nodular goiter with diffuse hyperplasia (TNGDH), and 105 toxic nodular goitre with nodular hyperplasia (TNGNH). The type of goitre was correlated to the development of disturbed thyroid function 1-6 years after surgery. Twenty-two patients with TDG and 18 (31 per cent) with TNGDH developed hypothyroidism; only 3 (3 per cent) with TNGNH showed hypofunction. Six patients with recurrent hyperthyroidism were found; all showed diffuse hyperplasia of the gland. It is concluded that the development of disturbed thyroid function after surgery is closely related to the histopathological type of goitre.

Adult↗
PubMed1980

Growth rate of giant-cell tumor of bone: radiographic and clinical considerations.

The progression of giant-cell tumor of bone was studied in 2 patients, a 16-year-old girl and a 26-year-old man with abnormalities of the cancellous bone in the distal femur. The tumors had been overlooked in the first roentgenographic examination, and the patients were discharged without treatment. In the girl, the tumor grew from 33 cm3 to 85 cm3 in 65 days, and in the man from 11 cm3 to 175 cm3 in 311 days before the lesions were diagnosed. The high rate of growth of these neoplasms reflects the inherent malignancy of giant-cell tumors around the knee.

Adolescent↗
PubMed1979

Experimental and clinical evaluation of cholangiography with xeroradiography.

Conventional screen film radiography is compared with xeroradiography in an experimental model for cholangiography. The wider exposure latitude of the xerographic technique confers certain diagnostic advantages. However, the actual clinical application presents practical difficulties, which, combined with low sensitivity, are of such a nature that the method can hardly be considered suitable at the present time. If certain improvements can be made, xeroradiography could become a superior method for radiography of the bile ducts.

Animals↗
PubMed1979

Bile duct diameter and diagnostic reliability at cholangiography.

Cases of exploratory choledochotomy with widened bile duct as the indication have been assessed with respect to missed bile duct concretion in a retrospective study covering a period of five years. During this period 2,000 cholecystectomies were performed. The 110 cases, in which (a) pre-exploratory cholangiography was completely normal apart from a diameter of more than 10 mm, (b) exploratory choledochotomy was performed, and (c) secondary cholangiography had been carried out, were studied in detail. No calculi were demonstrable either at exploratory surgery or secondary cholangiography. With a good radiographic technique it does not seem likely that bile duct concretions would be missed in widened ducts at otherwise normal operative cholangiography--at any rate not with bile duct diameters up to 20 mm.

Cholangiography↗
PubMed1979

Calcium infusion in suspected hyperparathyroidism: changes in parathyroid hormone concentration related to histopathological findings.

Changes in parathormone, total and free calcium concentrations in serum were studied in 27 patients with suspected hyperparathyroidism (25 with normocalcemia judged from CaT). Six patients were classified as normals. In 21 patients neck explorations was performed. Patients with definite pathology in the parathyroid glands had higher parathormone, total and free calcium levels than patients with borderline pathology or normal glands. The mean parathormone concentration fell significantly during calcium infusion in patients with histologically normal parathyroid glands. In patients with definitely pathological glands the parathormone concentration remained unchanged during the calcium infusion.

Adenoma↗
PubMed1979

Peroperative estimation of the size of the thyroid remnant.

A new method for estimation of the size of the remaining tissue after thyroid resection is described. The method has been tested on cadavers and during lobectomy in a series of patients. It is shown that intraoperative quantification of the thyroid remnant can be performed mostly with +/- 0.5 g for an individual thyroid lobe with a coefficient of variation of +/- 7.6%. In patients with toxic nodular goiter and calcifications, however, the error might be larger due to the varying homogeneity of the thyroid tissue. In 73 patients with negative antibody titers operated on for hyperthyroidism it was shown that the size of the thyroid remnant was negatively correlated to the delta TSH, determined 6 weeks after the operation.

Cadaver↗
PubMed1979

Serum activity of ornithine carbamoyl transferase in patients operated with jejunoileal bypass for extreme obesity after pretreatment with aminoacids.

Increased blood level of the liver specific enzyme ornithine carbamoyl transferase (OCT) is known to be a sensitive indicator of liver cell damage. The effect of preoperative aminoacid infusion to obese patients before jejunoileal bypass due to obesity was studied in 7 patients. They had a significantly lower rise on OCT than eight patients receiving only 5.5% glucose. The result seems to indicate that the liver in an obese patient undergoing abdominal surgery is protected against damage by an infusion of aminoacids.

Amino Acids↗