[On the present status of research in tumor metabolism].
Explore the source record for details and available documents.
Adenosine Triphosphate↗
Biomedical subjects
E Heise
Publications and source records attributed to E Heise.
Leukoencephalopathy after cisplatin therapy.
Cisplatin is a neurotoxic chemotherapeutic agent known to cause sensory peripheral neuropathy or ototoxicity. We report a patient with an oropharynx carcinoma who developed a multifocal, necrotizing leukoencephalopathy after cisplatin treatment. This indicates that cisplatin can induce, similar to other chemotherapeutic agents, demyelinating, necrotizing lesions in the white matter of the cerebrum.
Carcinoma, Squamous Cell↗
[Metabolism in the neoplastic cell].
Explore the source record for details and available documents.
Carbohydrate Metabolism↗
Estradiol receptor activity in human breast cancer, disease free interval and survival time.
Disease-free interval and survival time of breast cancer patients were investigated in regard to the estradiol receptor (ER) status as measured in the corresponding primary tumours. Disease-free interval and survival time of patients with ER positive breast cancers were found to be significantly longer than those of patients with ER negative tumours. The percentage of ER positive tumours in patients with finished free interval, or that died as a consequence of their disease, is lower than that found in an unselected material. The ER concentrations did not, however, differ significantly. Patients with ER positive breast cancers of stage IV did not survive longer than patients with ER negative tumours. No correlations could be found between disease-free interval and survival time of the patients, and the ER concentrations measured in their corresponding tumours individually. The menopausal status of the patients influenced the disease free interval regardless the ER status of the primary tumours. The survival time of postmenopausal patients with ER positive breast cancers were found to be significantly longer than that of premenopausal patients with ER negative cancers. The average ER concentration of breast cancers of postmenopausal patients with finished free interval is significantly higher than the valve found in cancers of premenopausal patients.
Breast Neoplasms↗