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Biomedical subjects

E Justich

Publications and source records attributed to E Justich.

At least 55 records · Page 3Linked to original sources

[Complications in 1000 cardiac catheter examinations in childhood].

Complications of cardiac catheterization of 1 000 subsequent investigations of pediatric patients were prospectively recorded. 18.2% of all patients presented in the newborn period with usual distribution of cardiac malformations of this age group. Total mortality was 1.8% within the first 24 hours. Newborn babies who were commonly hypoxic and in cardiac failure at the time of catheterization had a mortality of 9.3%. Causes of death were cardiac failure, hypoxia and severe arrhythmias. Comparing the first and second five hundred patients, mortality in the newborn seems to decrease with anaesthesia and ventilation of the patient. Increasing experience of the investigators and exclusion of non-operable malformations from catheterization by non invasive methods might also be responsible for this effect. The rate of arterial complications is 10% and high in our patients. Late venous thrombosis of the iliac veins and inferior vena cava in cyanotic malformations is one of the most serious problems. Apart from balloon atrial septostomy, the use of flow-guided balloon catheters in previous catheterizations could be responsible.

Adolescent↗

Radiographic scanning in barium examinations of the gastrointestinal tract.

The possibility of using radiographic scanning for gastrointestinal studies was evaluated experimentally. Two tubular barium-filled phantoms containing simulated ulcers and polyps were placed in a 25-cm water container, and radiographs made with the conventional technique and scanographic technique were compared. Images obtained with the radiographic scanner were superior in contrast and sharpness. Two-millimeter polyps could be easily detected in the larger phantom. Due to improved latitude the larger phantom could be adequately penetrated without overexposing the smaller phantom. This was not possible with the standard technique. Best results were obtained with a heavily filtered 140-kVp beam. Radiographic scanning has great promise in barium examinations of the gastrointestinal tract.

Barium Sulfate↗

[Tumor diagnostic by ERPC and its correlation to pathology (author's transl)].

In relation to 170 pancreatic and bile duct neoplasms confirmed by histology, the radiological signs were correlated to anatomical findings. The roentgenograms were analysed with regard to diagnostic accuracy, size of tumor and operability. 13 319 autopsies of the same period were screened in order to ascertain false positive and as well false negative findings in ERPC. Pancreatic tumors with a diameter over 3 cm were correctly found by ERPC in 98,4%, tumors below 3 cm in diameter in 75%. The over-all diagnostic accuracy for malignant tumors was 90,0%. There were no pathological findings in ERPC in two cases of pancreatic cancer with diameter below 3 cm. 10,5% of all pancreatic neoplasms were operable. Tumors of extrahepatic bile ducts all were discovered by ERPC but all of them were already inoperable.

Aged↗

[Experience with endoscopic papillotomy (author's transl)].

The results of 64 endoscopic papillotomies (EPT) are reported. When precautions are taken the EPT is a highly effective procedure of low risk. The minimal stress for the patient, the high accuracy and the low number of complications guarantee this method a prominent place in the treatment of bile duct illnesses. Control examinations of 30 patients to 12 months after operation proved all patients symptom-free and neither biochemical nor clinical evidence of cholangitis or other complications.

Adult↗

[Proof of the jejunogastric bile reflux after BII partial gastrectomy using 99mTc diethyl-IDA (author's transl)].

A history was obtained and barium meal and gastroscopy performed on 42 patients after a Billroth II partial gastrectomy. In order to demonstrate and quantify jejuno-gastric bile reflux, hepato-biliary sequential scintigraphy was carried out using 99mTc diethyl-IDA. The method has advantages over conventional techniques in that it is easy for the patient and demonstrates reflux both when the stomach is empty and full. The result showed that all patients who had evidence of inflammatory changes or ulcers on barium meal or gastroscopy had evidence of reflux.

Adult↗

Scanography with rotation of the radiographic tube: a new method.

The quality of the radiographic image is compromised by secondary radiations and geometric unsharpness, which is proportional to the focal spot size. The authors describe a new system which significantly improves both elimination of scatter and reduction of the apparent focal spot size and gives superior radiographs to those made with a conventional x-ray machine. Advantages of the new system include (a) the lack of resolution and density gradients across the radiograph, (b) increased contrast due to descreased scatter, (c) increased resolution, (d) possible routine radiography with a 100-mu focal spot, (e) up to 2.5 x magnification, (f) increased acceptable kVp range, and (g) decreased dose to the patient.

Humans↗

Routine magnification lymphangiography with a swinging slot X-ray machine.

Bilateral pedal lymphangiography was performed in 85 patients. Anteroposterior, lateral, and oblique views of the pelvis and abdomen were obtained with conventional radiographic technique and compared with 1.8 X magnification views obtained with a radiographic scanner that had a multiple slot system and with magnification views obtained with a standard 0.3-mm focal spot and a 12:1 grid.

Humans↗

[Importance of computer tomography in paediatric diagnostics of abdominal and pelvic tumours (author's transly].

In a joint study conducted by the University Clinic of Radiology, Graz, and the Medical University Clinic, Innsbruck, the results of computer tomography examinations of the abdomen and pelvis in 23 cases of tumours in children are discussed. In children, computer tomography resents special difficulties on account of the very poorly developed fatty layers between the organs and the increased incidence of movement artifacts. The importance of computer tomography for the diagnosis of abdominal and pelvic tumours is discussed.

Abdominal Neoplasms↗

[Contrast amplification of the liver parenchyma in the computer tomogram by using intravenous and peroral biliary contrast media (author's transl)].

If intravenous, biliary contrast media are used, a slight albeit specific enhancement of contrast of the liver parenchyma occurs with the applied dosage, which can be utilised in individual cases, for example for identifying isodense lesions. Contrast amplification by the peroral cholegraphic agent under examination, is insufficient for use in computer tomography of the liver. The use of biliary contrast media usually enables very good visualisation of the extrahepatic bile ducts. Attention is drawn to the possibility of pharmakokinetic studies by means of computer tomography.

Administration, Oral↗

[Endoscopic sphincterotomy and removal of a gallstone from the common bile duct (author's transl)].

Twenty-one patients with an average age of 69 years were subjected to endoscopic sphincterotomy of the papilla of Vater over the past six months. This therapeutic approach was successful and without ensuring complications in 20 of these patients. Hence, endoscopic sphincterotomy can be recommended in the case of elderly or high-risk patients as an alternative form of therapy to surgery with the attendent dangers of anaesthesia and, in particular, duodenotomy. However, it is unlikely to become a routine procedure since a team of highly-experienced specialists in endoscopy is mandatory with the close cooperation of radiologists and surgeons. The technique, indications and complications are mentioned.

Age Factors↗

[Cytodiagnosis of pancreatic juice and gall (author's transl)].

In 260 cytologic examinations of pancreatic juice and gall we were able to make a reliable diagnosis in 75%. 90% of the samples were taken before an ERCP. In the cytogram the cells of the gall passages, of the duodenum, and of the pancreas are easily distinguishable. Degenerative pancreas epithelia appear not only in pancreatitis but also in pancreatic carcinoma. 78% of the cases of pancreatic cancer were cytologically positive. By combining cytological examination with ERCP we can attain a large degree of reliability in the detection of cancer.

Bile↗

[The diagnosis of pancreatic carcinoma by combined endoscopic retrograde pancreatiography, aspiration cytology and carcinoembryonic antigen determination in the pancreatic secretion (author's transl)].

The reliability of diagnostic procedures in pancreatic disease can be significantly increased by the combination of endoscopic retrograde pancreaticography, determination of carcinoembryonic antigen and cytological examination of the aspirated pancreatic section. In the present study all cases of pancreatic carcinoma were correctly diagnosed by these methods. These combined diagnostic procedures seem to provide the basis for potential progress in the diagnosis of pancreatic carcinoma.

Carcinoembryonic Antigen↗

[Varicosities of the renal veins, the renal pelvis and the ureteric veins (author's transl)].

Varicosities of the renal veins and of the veins of the upper urinary tract may occur with or without haematuria. The urogram may be negative. Frequently, however, there are single or multiple impressions on the ureters as a result of the venous varicosities. Arteriography, which should always be carried out in the presence of undiagnosed haematuria, is unable to demonstrate the venous abnormalities. Since the symptoms are also not characteristic, it is necessary to carry out renal vein pharmaco-phlebography. The clinical features, radiological appearances and aetiology of this rare condition are illustrated by three cases.

Adult↗

[Serum lipase activity and evocation test after endoscopic retrograde cholangio-pancreatography (author's transl)].

Serum lipase activity, which is a more specific indicator of pancreatic damage than serum amylase activity, was determined in 51 patients before and immediately after endoscopic retrograde cholangio-pancreatography (ERCP) and 24 hours subsequently. An increase in serum lipase activity without clinical signs of acute pancreatitis was observed immediately after pancreatography in 20 cases. Increased serum lipase activity after 24 hours is largely observed in patients with parenchymography or those displaying increased values already in the fasting state before ERCP. This observation emphasizes the need for caution in the assessment of the indication for ERCP in patients with preexisting increased serum lipase activity in view of the very real risk of acute pancreatitis and the need to avoid parenchymography of the pancreas. According to our experience the addition of a broadspectrum antibiotic such as gentamycin to the contrast medium may, to a large extent, avoid the development of acute pancreatitis. Lipase evocation tests carried out 10 days after the ERCP showed negative results in patients with increased enzyme activity and parenchymography after pancreatography. Hence, it is concluded that ERCP causes symptomless reversible biochemical pancreatic changes, as opposed to irreversible pancreatic damage.

Acute Disease↗