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F Algaba

Publications and source records attributed to F Algaba.

At least 91 records · Page 5Linked to original sources
PubMed1987

Value of in vivo mucosa-staining test with methylene blue in the diagnosis of pretumoral and tumoral lesions of the bladder.

An in vivo staining test, methylene blue was applied to 50 patients with bladder tumor. 378 biopsies were performed in 85 areas stained with methylene blue and in 293 random biopsy areas. Of these samples, 56 had carcinoma in situ: 38 of these were not stained (68% false-negative) and the remaining 18 took up the stain. In the latter corresponding to 11 patients, carcinoma in situ was also shown in unstained areas examined by random biopsies. In 37 areas with urothelial dysplasia, 31 were not stained (84% false-negatives) while 6 cases (16%) took up the stain. Bladder tumors were stained in an irregular way but the intensity of the stain was related to the tumor grade. According to our experience the in vivo staining test with methylene blue cannot be used as a marker for pretumoral and tumoral lesions of the bladder.

Adult↗
PubMed1987

Renal oncocytoma: a true clinical entity?

Seven cases of renal oncocytoma, representing 4.10% of nephrectomies for tumors of the renal parenchyma between May 1978 and May 1985, are presented. From a thorough analysis of the literature and a comparison of these cases with well-differentiated, noninvasive clear-cell carcinomas, it can be concluded that renal oncocytoma is a variant of the wide spectrum of renal carcinomas. Hence, its clinical and therapeutical approach must not differ from that of the rest of the parenchymatous renal tumors.

Adenocarcinoma↗
PubMed1987

Value of random endoscopic biopsy in the diagnosis of bladder carcinoma in situ.

The data obtained from 2,272 random biopsies performed on cystocopically normal mucosa in 457 cases of primary bladder tumors, that did not undergo any previous treatment, are present. Dysplasia was found in 119 cases (26.04%) and carcinoma in situ in 100 cases (21.88%). The relationship between cancer in situ and tumoral grade was: G1, 4 of 76 (5.26%); G2, 33 of 225 (14.66%), and G3, 58 of 152 (38.16%). The relationship between cancer in situ and tumoral stage for superficial tumors (pTa-pT1) was 52 of 314 (16.56%), and for deep tumors (pT2, pT3, pT4), 42 of 109 (38.53%). In this least group of 109 cases, 53 cystectomies were performed and the diagnosis obtained by random biopsy and mapping of the surgical sample were correlated. A coincidence in both techniques was found in 77.36% of the cases.

Adolescent↗
PubMed1987

Origin of high-grade superficial bladder cancer.

The study of 12 patients with superficial G3 bladder carcinoma shows a high incidence of carcinoma in situ in the flat mucosa (66.6%, p less than 0.001), with a polypoid growth pattern (58.3%) and an evolution similar to isolated carcinoma in situ of the bladder. These data support the hypothesis that this variant of tumor is the expression of a vesical carcinoma in situ diagnosed at the time of intraluminal growth and therefore with its own capacity to become an infiltrative carcinoma.

Adult↗
PubMed1986

Balanitis xerotica obliterans in children.

This report is based on 7 children with balanitis xerotica obliterans. Of these patients 5 had stenosis of the urethral meatus that required meatotomy and the postoperative results were good. The frequency of balanitis xerotica obliterans in children at our center, as well as the findings of other authors, suggests that possibly more cases would be diagnosed during infancy if all dried foreskin were examined systematically.

Adolescent↗
PubMed1986

Small kidney and hypertension: selection of patients for surgery.

We studied 37 patients with various degrees of hypertension and a small unilateral kidney. Renal vein renin studies were shown to be positive on 19 occasions and negative on 18. Of those positive, 10 had severe and 1 moderate hypertension. Surgery cured 63.3%. In 27% blood pressure improved and 1 patient failed to respond. Eight patients had mild hypertension with a positive renal vein renin ratio (RVRR), but on observation their home blood pressures were normal without medication and they were not considered for surgery. Eighteen patients with mild hypertension and negative RVRR were also not operated. We believe that RVRR is important for a surgical decision, but only in severe and moderate hypertensives. In mild hypertension, measurement of blood pressure at home is normal on most occasions. These are hyperreactive patients and should not have surgery, regardless of the results of their RVRRs.

Adolescent↗
PubMed1986

Testicular pseudolymphoma.

Pseudolymphomas are reactive processes which by their morphology can be confused with lymphomas. They have been described in non-lymphoid organs (gastrointestinal tract, lung, breast, etc.), although cases have also been reported in the spleen. In this article we present the case of a 3-year-old child in whom the location was in the testes. It is the 4th case reported in the literature and the first in a child. The main criteria for establishing such a diagnosis are the delimitation of the lesion, the presence of mature lymphocytes intermingled with other cells which are mainly plasma cells of polyclonal type and the formation of lymphoid follicles with active germinal centers. A differential diagnosis within the testicle should be made with the lymphoma (primary or secondary), the leukemic infiltration and the seminoma with marked stromal lymphoid reaction.

Child, Preschool↗
PubMed1986

[Preventive chemotherapy of superficial tumors of the bladder].

A retrospective study of 135 patients with superficial transitional cancer of bladder (pTa - pT1) was conducted after follow-up for at least 3 years following treatment for 2 years at the "Instituto de Urología, Nefrología y Andrología (Fundación Puigvert)". Patients had been randomly allocated for treatment with: RTU alone, RTU + instillation of Thiotepa and RTU followed by instillations of Adriamycin. Chemotherapy was administered preventively. Recurrence after 3 years and possible progression towards infiltration during this period were evaluated, and the usefulness of this type of treatment questioned because of the cost/benefit ratio and small intergroup differences found.

Administration, Topical↗
PubMed1985

Transitional cell carcinoma of the prostate.

5 cases of transitional cell carcinoma of the prostate, which represent 1.5% of a series of 323 consecutive prostatic carcinomas, are presented. The cases with possible prostatic involvement by contiguity from a bladder carcinoma as well as those tumors with a transitional pattern which contain prostatic acid phosphatase in the cellular cytoplasm have been ruled out to make the diagnosis. The mean age of the tumoral onset is 70 years with an identical symptomatology to that of the adenocarcinoma. In 20% of the cases it is associated with an adenocarcinoma and in 40% with a bladder carcinoma without contiguity. The mean survival is 10.6 months with 60% succumbing within the first 6 months. Our findings agree with all authors in considering this type of tumor an urothelial neoplasia.

Acid Phosphatase↗
PubMed1984

Renal tuberculosis and hypertension: value of the renal vein renin ratio.

We applied the central renal vein renin ratios in a group of patients with unilateral renal tuberculosis and hypertension to see whether the diseased kidney was involved in the pathogenesis of the elevated blood pressure. Of 20 patients 11 were nephrectomized, 7 had positive renal vein renin ratios and normal peripheral plasma renin activity; only 2 kept their blood pressure in control without medication. From 5 without a positive index, only 1 kept his blood pressure in control without medicine 1 year after surgery. The renal vein renin ratio has to be interpreted in light of other parameters, such as blood pressure, peripheral renin--if high the more the chance of being significant--and global renal function. The renal vein renin ratio alone per se gives poor information on the pressor role of a unilateral tuberculous kidney.

Adult↗
PubMed1983

Metastatic tumor of the epididymis and spermatic cord.

We report a case of adenocarcinoma of the tail of the pancreas which was manifested by metastases to the spermatic cord and epididymis. 8.1% of the malignant tumors of the spermatic cord and/or epididymis are metastatic. After reviewing the literature on this subject, we found that the most frequent primary tumors metastatic to the spermatic cord and epididymis are carcinomas from the stomach (42.8%) and the prostate (28.5%). 23.8% of these metastases are subclinical and when discovered the wrong diagnosis is always made concerning the origin of the primary tumor. Only uncommonly (9.5%) are they the first sign of an occult neoplasm. In 47.6% of the cases, the metastases and the primary tumor are found simultaneously. The average survival, subsequent to the diagnosis of the metastasis, is 9.1 months.

Adenocarcinoma↗
PubMed1983

Effectiveness and morbidity of secondary retroperitoneal lymph node dissection after chemotherapy in testicular tumors.

Addition of surgery to cytoreductive chemotherapy has increased the number of patients with complete remission after advanced testicular cancer. In this report, we present the morbidity of complete retroperitoneal lymph node dissection following aggressive chemotherapy in 10 of these patients. Although no mortality and no postoperative major complications were registered in our series, there were high morbidity rates during operation represented by single or multiple dehiscences of the inferior vena cava and/or renal vein (7 cases), aortic graft for aortic dehiscence (1 case), partial sigmoidectomy after inferior mesenteric artery division (1 case with previous retroperitoneal radiotherapy), total nephrectomy (2 cases), and suprarenalectomy (5 cases). Because the overall possible benefit of chemotherapy-surgery combination was seen in 7 of our 10 stage III-B4 patients, we believe that the combined approach is the best option for treating advanced retroperitoneal testicular cancer and its results justify the morbidity due to lymphadenectomy.

Adult↗
PubMed1983

[Isolated hematurias: histologic and immunologic study].

An immunologic study and a renal biopsy were performed in 64 patients with isolated hematuria. Fifty of them had macroscopic hematuria and 14 microscopic hematuria. The kidney was normal in 66% by light microscopy; in the remaining 34% glomerular lesions were moderate: thickening of the mesangial matrix, diffuse or segmentary mesangial proliferation. Four patterns were observed by immunofluorescence: C3 located either in the mesangium, or at the level of the vascular pole, mesangial IgA, mesangial IgM and lack of deposits. According to our experience IgA nephropathy presenting as isolated hematuria has a better prognosis than the other symptomatic forms of this glomerulonephritis. No patient with the other renal pathological changes so far developed hypertension or renal failure. We prefer to perform biopsies on patients with isolated hematuria, considering the frequency of IgA nephropathy and the possibility of finding mesangial deposits of IgM and C3 whose significance is so far poorly known.

Adolescent↗
PubMed1983

[Isolated renal angiomyolipoma. Study of 10 cases].

The authors review 10 cases of isolated renal angiomyolipoma collected from the archives of the Institute of Urology, Nephrology and Andrology, Barcelona, Spain (Fundacion Puigvert) which contain a total of 170,000 records collected between 1930 and 1980. They describe the clinical, laboratory, histopathological and therapeutic characteristics, as well as the course of the cases studied in comparison with parenchymatous renal tumours, angiomyolipomas accounting for 2.07%. The attention of the reader is drawn to the fact that all the cases presented here were of isolated renal angiomyolipomatosis, in the absence of any context of phakomatosis and no possibility of preoperative diagnosis by conventional methods of investigation. It is felt that a preoperative diagnosis would be possible by computed tomography using the scanner by virtue of the adipose content of the angiomyolipoma.

Adult↗
PubMed1981

Fibrous polyp of the ureter.

The most frequent ureteral tumors are transitional carcinoma. Benign neoplasms are uncommon. In this paper we present 6 cases of ureteral polyps, which represent 11.1% of all the tumors in our series of ureteral tumors. We have reviewed the possible etiopathogenesis and exposed the clinical characteristics. Secondary to the obstructive phenomenon and the radiologic signs, it is the tigroid appearance, the localization and the absence of total obstruction which allows the diagnostic suspicion. The treatment of choice is partial resection. Ureterostomy with peroperatory biopsy, in cases in which the malignancy is not yet established, is recommended in order to avoid unnecessary nephroureterectomies.

Adult↗