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Biomedical subjects

H Winkelmann

Publications and source records attributed to H Winkelmann.

At least 37 records · Page 2Linked to original sources
PubMed1987

[Significance of scanning electron microscopy observations on cellular reactions in the biological evaluation of endoprosthetic materials].

In a scanning electron microscopic study there are described the adhesion, spreading and formation of confluent monolayers from fibroblasts and epithelioid cells on Al2O3-ceramics and cobalt-basis-alloys in relation to vitreous carbon and glass. The morphogenetic reactions of cultured cells were not significantly different in pattern, behaviour and kinetics on various biomaterials. The cells adhered, spread, migrated and proliferated on the surface of biomaterials to be tested. This allows the conclusion that this implant material is compatible with cells. The variability of properties and susceptibility of cultured cells were discussed as a criterion for biocompatibility of implant materials in preclinical test.

Animals↗
PubMed1986

[Neurosurgical aspects of the treatment of esthesioneuroblastoma].

On the basis of the example of two observations by the author the diagnostic and therapeutical problems of the esthesioneuroblastoma are discussed. Neurosurgical problems result from the growing of the tumor into the inner space of the skull or the destruction of the anterior base of the skull with subsequent inflammatory consequences.

Adult↗
PubMed1984

[Morphological studies of triton-extracted cultured cell cytoskeleton].

The Coomassie Brillant Blue method of Pena (1980) was modified by use. The used method is simple and versatile for the investigation of morphological phenomena on the whole cytoskeleton of different cells in vitro. The additional advantage is the use of the specimens for the scanning electron microscopic observation after critical-point drying.

Animals↗
PubMed1983

Nystatin- and amphotericin B-induced structural alterations of the erythrocyte membrane: importance of reduced ionic strength.

The effect of the polyene antibiotics nystatin and amphotericin B on the membrane structure of human erythrocytes has been investigated by freeze-fracture electron microscopy. Nystatin induces the same particlefree elevations on the erythrocyte membrane as already observed after treatment with amphotericin B. This structural alteration appears only in presence of an isotonic medium with reduced ionic strength. The dependence on the ionic strength supports the interpretation of these structures to be lipid domains.

Amphotericin B↗
PubMed1983

[Neuroradiologic diagnosis of diastematomyelia].

A report is given on 5 patients with diastematomyelia, in one case the fissure formation of the marrow being without a provable septum. In the frequently very complex pathological-anatomical conditions of the spinal dysraphic malformation, CT can be a considerable help. In combination with metrizamide myelography, details of the marrow parts and their envelopes can be demonstrated. The preoperative planning of the marrow separation becomes more exact. Other causes of a deep spinal marrow level (tethered cord) such as teratomas can also be recognized by CT.

Diagnosis, Differential↗
PubMed1981

[Surgical treatment of occlusive intracranial cerebrovascular disorders (author's transl)].

Management of intracranial cerebral circulatory disorders represents a relatively new interesting and delicate field in neuro--and vascular surgery. Today, we know the reconstructive and constructive microsurgical approach to brain vessels in man. Most surgeons practise the constructive procedure. The authors criteria for selection of patients are presented. The aim of surgical therapy is to increase the blood flow because retrograde blood supply by the collateral system is anatomically or functionally insufficient.

Aged↗