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Biomedical subjects

J F Orr

Publications and source records attributed to J F Orr.

At least 37 records · Page 2Linked to original sources

Development of a computer model to predict pressure generation around hip replacement stems.

Cemented fixation of hip replacements is the elective choice of many orthopaedic surgeons. The cement is an acrylic polymer which grouts the prostheses into the medullary cavity of the femur. Cement pressure is accepted as a significant parameter in determining the strength of cement/bone interfaces and hence preventing loosening of the prostheses. The aim of this work was to allow optimal design of the intramedullary stem of a hip prosthesis through knowledge of the flow characteristics of curing bone cement which can be used to predict pressures achieved during insertion of the femoral stem. The viscosity of the cement is a vital property determining the cement flow and hence cement interdigitation into bone. The apparent viscosities, nu(a), of three commercial bone cements were determined with respect to time by extrusion of the curing cement through a parallel die of known geometry under selected pressures. Theoretical models were developed and implemented in a computer program to describe cement flow in three models each of increasing complexity: (a) a simple parallel cylinder, (b) a tapered conical mandrel and (c) an actual femoral prosthesis, the latter models being complicated by extensional effects as annular areas increase. Predicted pressures were close to those measured experimentally, maximum pressures being in the range 10-160 kPa which may be compared with a threshold of 76 kPa proposed for effective interdigitation with cancellous bone. The theoretical model allows the prosthesis/bone geometry of an individual patient to be evaluated in terms of probable pressure distributions in the medullary cavity during cemented fixation and can guide stem design with reference to preparation of the medullary canal. It is proposed that these models may assist retrospective studies of failed components and contribute to implant selection, or to making informed selection from options in custom hip prosthesis designs to achieve optimum cement pressurization.

Bone Cements↗

The effects of increasing the reverse curve of Spee in a lower archwire examined using a dynamic photo-elastic gelatine model.

This paper describes the development and testing of a dynamic in vitro photo-elastic model for evaluating the effects of orthodontic mechanics on an entire arch of teeth. A model of a mandibular arch was made and the teeth were embedded in a gelatine material with a high level of mechanical creep which permitted tooth movement in response to orthodontic forces. The excellent photo-elastic properties of this material also facilitated the analysis of the stress distribution around the roots of the teeth. The model of a mandibular arch was used to investigate the tooth movements and stress distributions produced by increasing the reverse curve of Spee in a 0.018 x 0.025-inch stainless steel archwire. The results revealed that a 1-mm reverse curve of Spee increased the arch length by 1.6 mm, but increasing the reverse curve of Spee to 5 mm did not increase arch length further. Photo-elastic analysis showed an increased stress distribution around the roots of the incisors and molars as the reverse curve of Spee was increased in the archwire.

Birefringence↗

Photoelastic stress analysis in a pier retainer of an anterior resin-bonded fixed partial denture.

STATEMENT OF PROBLEM: A clinical situation may arise with 2 edentulous spaces and a single intact pier tooth. A dentist may restore these edentulous spaces with a long span resin-bonded fixed partial denture using the pier and the 2 terminal abutments for bonding. PURPOSE: This study analyzed the stresses induced in a pier retainer of an anterior resin-bonded fixed partial denture and determined the effect on a pier abutment. MATERIAL AND METHODS: Photoelastic materials were selected to represent the relative stiffness of 3- and 5-unit resin-bonded fixed partial dentures. The models were scaled to x2.5 to enhance visual analysis of the stress pattern. RESULTS: Isochromatic fringes indicated a stress magnitude at the proximolingual areas of the pontic in the 3-unit resin-bonded fixed partial denture. In the 5-unit resin-bonded prosthesis, the stress pattern appeared to involve the entire surface of the pier retainer. CONCLUSION: The use of pier abutments should be avoided and it is more favorable to use 3-unit resin-bonded fixed partial dentures.

Dental Abutments↗

Capsulated versus hand-mixed glass-ionomer luting cements for post retention.

OBJECTIVES: Glass-ionomer luting cements are supplied in two forms, as loose powder and liquid to be hand-mixed (HM) or pre-proportioned in a capsule to be mechanically mixed (MM). This study was to determine if post retention in pull-out tests was affected by the method of mixing the cement. METHODS: Two hundred stainless steel posts of diameter 1.75 mm were cemented within post-channels prepared in stainless steel cylinders using two hand-mixed cements FJL and KCL (Fuji I Luting Cement and Ketac-Cem Luting Cement) and two capsulated cements FJC and KCM (Fuji Cap I and Ketac-Cem Maxicap). Three groups of test specimens were prepared. In Group I each cement was mixed as recommended by the manufacturer, Group II cements were placed within a capsule and mechanically mixed and in Group III cements were removed from the capsule and mixed by hand. Specimens were stored for 1 h at 37 degrees C and 100% humidity prior to post pull-out tests at a crosshead speed of 10 mm min-1. The maximum loads at failure were subjected to Weibull analysis and Mann-Whitney tests to determine probabilities of survival and significant differences between the groups. RESULTS: Significant differences (P < 0.05) were found between all pairs of cements tested except KCM(MM) vs FJL(HM), FJL(MM) vs KCL(HM), KCL(MM), vs KCL(HM), FJC(HM) vs FJC(MM), KCL(MM) vs FJL(MM). CONCLUSIONS: The capsulated cements as supplied by the manufacturers are preferable to the equivalent hand-mixed formulations, as they give higher probabilities of survival when subjected to a given load. Both capsulated and hand-mixed formulations of Fuji had higher probabilities of survival compared to the corresponding Ketac cements. The probability of post survival can be altered by the method of mixing the cement.

Capsules↗

Comparison of conventional and resin-modified glass-ionomer luting cements in the retention of post-crowns by fatigue loading.

Fatigue testing may be used for in vitro evaluation of luting cements, allowing comparison of materials under controlled conditions. It is recognized that glass-ionomer cements are materials which are susceptible to microcracking, even during curing prior to load application, and their failure can be related to crack propagation. The aim of this study was to compare the retention of post-crowns cemented with conventional and resin-modified glass-ionomer cements, the latter having significantly greater fracture toughness, under cyclic loads which are representative of physiological service. A custom-designed fatigue machine was used for three tests each comprising 18 specimens in a modified randomized complete block programme. Correlation of load amplitude to endurance was low, as expected from static test experience, but cement comparison was made through Kaplan-Meier survival and cumulative hazard functions. Differences in the performance of the cements were indicated, but were not statistically significant in this study, although analysis by Cox's proportional hazards model indicated that significance may be gained by a larger study.

Acrylic Resins↗

Flow characteristics of curing polymethyl methacrylate bone cement.

During polymerization, polymethyl methacrylate bone cements have complex viscoelastic characteristics. Within a short working time they transform from dough-like consistencies to solid cements. Therefore, the time at which a cement is introduced to cancellous bone surfaces and subjected to pressure is important, to achieve optimum flow and mechanical interdigitation. Achieving adequate mechanical interlock increases the area for load transfer and reduces localized bone-cement interface stresses. The aim of this study was to measure the flow characteristics for commercial bone cements as a function of time and calculate the apparent viscosities for the curing bone cements. The capillary extrusion method was used to measure the rate of flow of the curing cement, by means of a melt flow index apparatus, which was manufactured in-house. The tests were conducted using nozzles of different lengths and under two loads. This enabled the power index value, n, and the pressure at the die entry, P0, to be calculated for each material with respect to time. Once the flow characteristics were determined, a series of formulae were used to calculate the shear rates, gamma, the shear stresses, tau, and the apparent viscosities, eta a, of the curing bone cements. The results indicated that acrylic bone cements are non-Newtonian, pseudoplastic materials, since the power index values are less than 1.0 during the curing stage. The consistency indices, K, were calculated from the shear stress versus shear rate data. The apparent viscosities of the cements were found to increase with respect to increases in time. Clinically, it was considered desirable to inject and pressurize the cement into the medullary canal while its viscosity is relatively low in order to obtain maximum interdigitation into cancellous bone, provided adequate containment and a means of pressurization can be achieved. The pseudoplastic character of bone cements is responsible for their reduction in viscosity with increased shear rate, a property that may be exploited to enhance penetration with appropriate delivery.

Biocompatible Materials↗

The evaluation of post-retained crowns using a custom-designed fatigue machine.

There are many published reports of static tests on dental materials that are required to perform clinically under a range of load amplitudes and cyclic frequencies. There are fewer reports in the dental literature of fatigue tests on dental structures and materials, and these are reviewed in this paper along with a description of the design, manufacture and commissioning of a machine which can apply chosen cyclic load/time characteristics up to a maximum amplitude of 700 N and frequency of 5 Hz. The machine design is not specific to particular test specimens but is widely applicable within dental materials testing. The machine is being used for a continuing study of post-retained crowns, cemented with glass-ionomer cement. The planning of fatigue tests and the interpretation of results is discussed with reference to the experience of previous authors, and it is concluded that a survival analysis approach offers a means of understanding materials' performances. The initial results from a random, blocked comparison of three glass-ionomer luting cements indicated that cyclic loads can be identified to give a 50% survival probability for specimens. It is expected that loads experienced in vivo have lower amplitude than those applied in this study, however, such loading cycles have been chosen to facilitate material comparisons. It is concluded that gaining significant results under laboratory fatigue conditions is difficult, but that they may usefully complement clinical trials.

Animals↗

Factors influencing the failure of dental glass ionomer luting cement due to contraction.

Glass ionomer cement used to fix a post within the root of a tooth undergoes cohesive failure on setting. This study aimed to determine the importance of humidity, substrate material and post design on cement failure. Nine groups of five specimens were prepared: groups 1-3 addressed the influence of post design and sectioning process on cement failure, while groups 4-9 examined the interaction between the cement, substrates and humidity. Replicas were prepared of all specimens and viewed using scanning electron microscopy. It was concluded that humidity and substrate influenced the failure of glass ionomer cement whereas post design did not.

Animals↗

Photoelastic stress analysis in resin bonded bridge design.

The aim of this investigation was to determine the stress magnitudes and directions in resin bonded bridges. 3D models (2.5 x life size) were prepared from photoelastic materials that represented the ratio of the elastic moduli of enamel and metal. The models were loaded during a stress freezing cycle and sectioned to view in a transmission polariscope. The fringes observed, indicated that the stress magnitudes concentrated at the proximo-lingual line angles to the pontic. The stress trajectories were plotted to show the pattern of stress direction. The stress factors which may contribute to debonding of these designs were analysed. It is suggested that the use of vertical grooves at the proximolingual line angles to the edentulous area in the preparation should reduce the stresses and hence improve the long term prognosis.

Bicuspid↗

Comparative study of four glass ionomer luting cements during post pull-out tests.

OBJECTIVES: The aim of this study was to compare the maximum loads and modes of failure of four glass ionomer luting cements during post pull-out tests. METHODS: The cements studied included two based on conventional glass ionomer cement chemistry, i.e., a hand-mixed cement and an encapsulated cement, and two based on the newer light-cured chemistry, i.e., a restorative cement used at a low powder:liquid ratio and an experimental luting cement. One hundred and forty bovine incisors were cut 13 mm from the apex and prepared with post channels, 1.75 mm in diameter and 9 mm long. Ni-Cr-Mb bonding alloy posts were cast and sandblasted prior to cementation into the roots with each of the cements. Twenty-four hours later, pull-out tests were carried out at a strain rate of 0.5 mm/min. The maximum loads and modes of failure were noted. The data obtained were analyzed using a Kruskal-Wallis test followed by comparison of groups using Mann-Whitney tests. RESULTS: Comparison of the maximum loads revealed a significant difference between the conventional encapsulated cement and all other cements. Weibull analysis of the results gave values for the Weibull moduli and probabilities of survival for a post under a given load for each cement and indicated that the newer cements performed better than the conventional cements. SIGNIFICANCE: Further research into the in vitro and in vivo behavior of the resin-modified glass ionomer cements in clinical situations where light-curing is not possible is justified.

Acrylic Resins↗

Pressurization of bone cement under standard, flanged and custom acetabular components for total hip replacement.

Custom acetabular components are proposed to achieve uniform cement mantles, even in irregular acetabula presented at revision, in order to enhance fixation. One aim of developing custom components was to permit pressurization of bone cement by the components at insertion and maintain the pressure during polymerization. A model acetabulum was set up for the insertion of standard, flanged and custom components under constant force. Cement pressure was measured at the floor of the acetabulum by means of a piezoelectric diaphragm transducer. Polythene tubes were inserted in the model acetabular walls to estimate penetration of cement into cancellous bone. Insertion of the standard and flanged components caused cement pressures up to 106 kPa which decayed to less than 21 kPa as cement escaped at the rim and the components came into contact with the acetabulum. The custom component maintained a pressure of over 60 kPa during polymerization from an initial pressure of 105 kPa and examination of cement mantles on removal showed no evidence of contact. The custom component also showed enhanced penetration of cement, especially around the rim of the acetabulum. It is concluded that the custom component design achieves higher cement pressures and that better fixation will result.

Bone Cements↗

A semi-empirical model for prediction of how post-retained crowns will fail under compressive loading.

The aim of this in vitro study was to determine the relative contributions to retention of the different components of the post-retained crown and the mode of failure when the crown was loaded at 50 degrees to the vertical (i.e., in an apical direction). Failure was initiated in all the specimens as a rotation of the crown about a point on the labial surface of the root at the crown-root interface with pull-out of the post. A semi-empirical model was developed to explain this mode of failure. From experimental results, it was noted that the retention provided by the post was the most significant factor in the equation. However, large variation in the maximum forces recorded from pull-out tests on 40 posts suggested that the glass-ionomer cement was acting in the manner of a brittle composite material whose failure may be attributed to defects in the structure causing stress concentrations. The probability of survival at each ultimate strength recorded experimentally was plotted for comparison with the curve generated by the derived Weibull function. Close agreement was noted. Thus, for any given force applied compressively at 50 degrees to the vertical to a post-retained crown of known dimensions, it is possible, by use of the described equation, to calculate the force, P, applied to the post. This value of P may then be inserted into the Weibull equation to give the probability of the crown failing under that applied force.

Animals↗

An investigation into the fixation of hip replacements.

This paper describes an experimental study of hip prosthesis stems fixed with bone cement in model femora and subjected to cyclic loading. Loosening of the stems did not occur due to fatigue of the bone cement, even when reduction of medial support from the calcar had been simulated. Measurement of stresses in the cement layer and comparison with published properties of bone cement indicated that fatigue failure was not likely under the experimental conditions. Fatigue failure of cement could not be solely regarded as initiating loosening. It is concluded that the results uphold theories that biological factors must also contribute to the initiation of loosening, rather than being a response to mechanical failure.

Body Weight↗

Testing of total hip replacements: endurance tests and stress measurements. Part 1: Endurance tests.

This is a paper in two parts. Part 1 gives details of fatigue tests carried out on Howse II hip prostheses. Three types of tests were carried out in accordance with three different draft test standards. Standard (I) was BSI DD91: 1984 in which the load range is 0.3-4.1 kN and the antero-posterior offset angle is 15 degrees. Standard (II) was BSI DD91: 1986 where the load range is 0.3-2.3 kN and the offset angle is 9 degrees. Standard (III) was ISO/DP 7206/3 in which the load range is 0.3-4.1 kN and the offset angle is 0 degrees. Four specimens were tested according to each standard. It was found that all the specimens tested according to standard (I) failed by fatigue after less than 6 x 10(5) cycles. All the specimens tested according to standards (II) and (III) withstood 5 x 10(6) cycles without failure. It is clear that the offset angle has an important influence on the fatigue life of the prosthesis. It is concluded that tests according to standard (I) are too severe, while tests according to standards (II) and (III) are either adequate or lax. This led to Part 2 of the investigation where the stresses in the prostheses were measured and calculated.

Hip Prosthesis↗

Testing of total hip replacements: endurance tests and stress measurements. Part 2: Stress measurements.

Brittle lacquer techniques and electric resistance strain gauge rosettes were used to measure strains on the stems of total hip replacements while loaded according to three standards. The stresses in these locations were also calculated and good agreement was found between the measured and calculated values. The Sines equation was used to calculate the endurance limit stress. Again good agreement was found with observed results. Suggestions are made regarding the endurance testing of hip prostheses.

Hip Prosthesis↗

An investigation into the effect of cyclic loading and frequency on the temperature of PMMA bone cement in hip prostheses.

A titanium alloy hip prosthesis was inserted in a Tufnol tube representing the upper part of the femur. The prosthesis was cemented in the model femur using PMMA bone cement. Five thermocouples were embedded in the bone cement and the assembly was subjected to cyclic loading with a range of 0.3-4.5 kN at a frequency of 6 Hz. Temperature measurements over a 48 hour period indicated that the temperature rise in the bone cement was less than 4 degrees C. It is concluded that such tests can be carried out at 6 Hz without significantly affecting the mechanical properties of PMMA bone cement.

Bone Cements↗