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J Haot

Publications and source records attributed to J Haot.

At least 109 records · Page 6Linked to original sources
PubMedDate not supplied

[Anatomo-pathological classification of gastric tumors].

Pathological classification of gastric tumours. The authors propose a pathological classification of gastric tumours based on topography of lesions. The tumours are related to their origin and localization in the gastric wall: mucosal, extramucosal and metastatic. Among the mucosal tumours, the most frequent are benign polyps, mostly of the hyperplastic type. The classification of mucosal malignant tumours (adenocarcinomas) is dual: macroscopic and microscopic. From the macroscopic point of view, the authors recommend Borrman's classification for invasive cancer and Murakami's classification for early cancer. At the microscopic level, they suggest Lauren's classification in intestinal and diffuse forms or Ming's classification in expanding and infiltrating types. The decreasing incidence of gastric adenocarcinomas in Western countries has artificially increased the relative frequency of gastric lymphomas. The differential diagnosis with reactive lymphoïd hyperplasias may sometimes be troublesome for the pathologist. Among extramucosal tumours, the most frequent are stromal tumours, formerly called leiomyomas and leiomyosarcomas; most are benign. The criteria of malignity are: tumour size, focal necrosis, hypercellularity and mitotic index. The metastatic tumours are mostly melanomas and mammary carcinomas.

Gastric Mucosa↗
PubMedDate not supplied

[Immunological aspects of lymphocytic gastritis].

Diffuse and corporeal varioliform gastritis represent the usual endoscopic expression of lymphocytic gastritis. Referring to the work of other authors on varioliform gastritis, immunocytochemical studies have been made on the plasma cells of the lamina propria in two comparative series of lymphocytic and chronic atrophic gastritis. We could not demonstrate any significant variation in the number of IgE plasma cells between the two types of gastritis. In another study, the lymphocytic populations of the lamina propria and of the epithelium were characterized by peroxidase immunocytochemical methods on frozen sections. In agreement with other authors we confirmed that, in lymphocytic gastritis, the intraepithelial lymphocytes belong to the T group with a predominance of the T8 subgroup. In the lamina propria, the lymphocytes were mostly T with a slight preponderance of the T4 subgroup. B lymphocytes were scarce. The distribution of B and T lymphocytes was the same as that observed in coeliac disease.

Gastritis↗
PubMedDate not supplied

[Anatomopathological criteria of progression in chronic idiopathic colitis].

Idiopathic inflammatory colitis are diseases of remissions and exacerbations of various severity. The criteria of activity are based on a conjunction of clinical, radiologic, endoscopic and anatomopathological data. From the macroscopical point of view, they are different in ulcerative colitis and Crohn's disease. Ulcerative colitis is characterized by a diffuse and uniform mucosal inflammation; any biopsy outside an ulcerative area can be used to evaluate the inflammatory components which are in the acute phase (chronic active phase): oedema, vascular congestion and an inflammatory infiltrate composed of a mixture of lymphocytes, plasma cells and polymorphs with partial destruction of the glands (crypt abscesses). In the revolving phase, the inflammation regresses; the crypts are distorted, the crypt abscesses gradually disappear. In ulcerative colitis in remission, the inflammation vanishes but there is loss of parallelism and branching of the crypts. In Crohn's disease, the inflammation is often discontinuous and focal; biopsies must be taken from multiple sites. It is not rare to see a coincidence of lesions at different stages of activity. The criteria of activity are less reliable than in ulcerative colitis. Acute lesions present with oedema and infiltration of the lamina propria by polymorphs, neutrophils as well as eosinophils. Granulomas probably represent a particular reactional status. There features and number do not very significatively in the course of the disease.

Colitis, Ulcerative↗
PubMedDate not supplied

[Histology of colonic polyps].

The authors present the modern classification of colorectal polyps. They discuss the dysplastic and preneoplastic changes in the light of new data on predisposing factors. Although new techniques are developing such as immunocytochemistry, DNA cytophotometry, DNA recombination, it is clear that presently, the basic morphological data, microscopical as well as histological, retain an irreplaceable diagnostic value. From a practical point of view, the authors recall the importance of an adequate orientation of the polyps before their histological examination in order to obtain all the necessary informations permitting an accurate diagnosis: type of the polyp, possible areas of cancer formation and their depth of penetration, histology of the surrounding mucosa and tissues.

Cell Transformation, Neoplastic↗
PubMedDate not supplied

[Liposarcoma of the ischiorectal fossa, an unusual tumoral site].

The main locations of the liposarcoma, the most common of the soft tissue sarcomas, are the lower limbs and the retroperitoneal space. We report the case of a 58 year-old male patient presenting with a huge and painless mass of the left fossa ischiorectalis. Preoperative tests and CT-scan of the pelvis evoked the diagnosis of liposarcoma, laminating and lifting the rectum and bladder. Visceral walls were respected. The patient underwent a en-bloc excision of the tumour by a combined perineal and abdominal route. Pathological examination of the mass (1.7 kg) confirmed the diagnosis of well differentiated liposarcoma. No further treatment was initiated, but, because of the high risk of local recurrence, the patient has been placed under a close follow-up schedule.

Humans↗
PubMedDate not supplied

[Benign tumoral and pseudotumoral lesions of the stomach. Study of a surgical and biopsied series].

Benign gastric tumours and pseudotumours have often been a cause of confusion not only diagnostically but also in terms of treatment, since their significance varies with the histologic type. We try to provide a comprehensive classification scheme dividing gastric benign tumours and pseudotumours in 3 major categories: epithelial, mesenchymatous and dysembryoplastic. We review the clinical significance of the subcategories.

Choristoma↗
PubMedDate not supplied

[Radiological aspects of peri-diverticular disease of the colon. An anatomo-pathological correlation (author's transl].

Sixty consecutive cases operated for diverticular disease of the colon within the last 10 years are reviewed. A comparative study is made of the anatomopathological examination of the specimens and their radiological aspect trying to establish the precise radiological picture of acute, chronic and fibrotic peri-diverticular disease. Plain films of the abdomen, intravenous uro- and cystography are very useful in acute cases. A baryum enema just prior to surgery (33 cases) heralds by the rigid aspect of the involved bowelsegment the acute case; spasms, thick disorderly folds and localized extravasation characterize the acute peridiverticulitis. Fibrotic peri-diverticular disease shows disorderly, fine but "ragged" folds associated with extrinsic fistulae. In many cases the inflammation is not purely acute nor chronic or fibrotic. The distinguishing histological types are simultaneously present and render the radiological picture complex.

Barium Sulfate↗
PubMedDate not supplied

[Peridiverticulitis of the colon: confrontation of pre- and postoperative diagnosis (author's transl)].

The authors report their experience with the surgical management of the peridiverticulitis coli (60 cases). It is frequently uneasy to have an accurate pre- and peroperative diagnosis of the nature and the grade of severity of the illness. So, the indication for surgery, the choice of the procedure, and the evaluation of the results are somewhat subjective. The microscopical study of the resected colons give objective data about the status of the bowel. Our pathological findings have shown major inflammatory lesions in the colons which were resected in emergency, in the cases operated upon for stenoses and fistula. On the other hand, when patients underwent an elective surgical procedure, after a primary conservative (medical or surgical) treatment, the inflammation could be absent. The risks of leaving in place some of these colons seem to be small.

Abdomen, Acute↗