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Biomedical subjects

J R Heath

Publications and source records attributed to J R Heath.

At least 19 recordsLinked to original sources

Electrical addressing of confined quantum systems for quasiclassical computation and finite state logic machines.

Conduction spectroscopy measures the current I through a nanosystem as a function of the voltage V between two electrodes. The differential conductance, dI/dV, has peaks that can be assigned to resonance conditions with different electronic levels of the system. Between these increments, the current has roughly constant plateaus. We discuss how measurements of the current vs. voltage can be used to perform Boolean operations and hence construct finite state logic machines and combinational circuits. The inputs to the device are the source-drain voltage, including its sign, and a gate voltage applied in a manner analogous to optical Stark spectroscopy. As simple examples, we describe a two-state set-reset machine (a machine whose output depends on the input and also on its present state) and a full adder circuit (a circuit that requires three inputs and provides two outputs).

Journal Article↗

Quantum dot artificial solids: understanding the static and dynamic role of size and packing disorder.

This perspective examines quantum dot (QD) superlattices as model systems for achieving a general understanding of the electronic structure of solids and devices built from nanoscale components. QD arrays are artificial two-dimensional solids, with novel optical and electric properties, which can be experimentally tuned. The control of the properties is primarily by means of the selection of the composition and size of the individual QDs and secondly, through their packing. The freedom of the architectural design is constrained by nature insisting on diversity. Even the best synthesis and separation methods do not yield dots of exactly the same size nor is the packing in the self-assembled array perfectly regular. A series of experiments, using both spectroscopic and electrical probes, has characterized the effects of disorder for arrays of metallic dots. We review these results and the corresponding theory. In particular, we discuss temperature-dependent transport experiments as the next step in the characterization of these arrays.

Journal Article↗

Molecular-based electronically switchable tunnel junction devices.

Solid-state tunnel junction devices were fabricated from Langmuir Blodgett molecular monolayers of a bistable [2]catenane, a bistable [2]pseudorotaxane, and a single-station [2]rotaxane. All devices exhibited a (noncapacitive) hysteretic current-voltage response that switched the device between high- and low-conductivity states, although control devices exhibited no such response. Correlations between the structure and solution-phase dynamics of the molecular and supramolecular systems, the crystallographic domain structure of the monolayer film, and the room-temperature device performance characteristics are reported.

Journal Article↗

Tooth preparation.

This final article in the series describes the modification of teeth to improve their shape for the support and retention of RPDs.

Denture, Partial, Removable↗

Initial prosthetic treatment.

This article describes measures designed to provide short-term solutions to existing RPD problems and to establish an optimum oral environment for the provision of definitive prostheses.

Denture Rebasing↗

Connectors.

This article describes the types and functions of connectors for RPDS. It also considers the relative merits and limitations of these connectors.

Acrylic Resins↗

Indirect retention.

This article explains the mechanism of indirect retention for RPDs and discusses the factors which determine its effectiveness. Examples are given of designs which incorporate indirect retention.

Dental Abutments↗

Clasp design.

Explore the source record for details and available documents.

Dental Clasps↗

Bilayer reconstitution of voltage-dependent ion channels using a microfabricated silicon chip.

Painted bilayers containing reconstituted ion channels serve as a well defined model system for electrophysiological investigations of channel structure and function. Horizontally oriented bilayers with easy solution access to both sides were obtained by painting a phospholipid:decane mixture across a cylindrical pore etched into a 200-microm thick silicon wafer. Silanization of the SiO(2) layer produced a hydrophobic surface that promoted the adhesion of the lipid mixture. Standard lithographic techniques and anisotropic deep-reactive ion etching were used to create pores with diameters from 50 to 200 microm. The cylindrical structure of the pore in the partition and the surface treatment resulted in stable bilayers. These were used to reconstitute Maxi K channels in the 100- and 200-microm diameter pores. The electrophysiological characteristics of bilayers suspended in microchips were comparable with that of other bilayer preparations. The horizontal orientation and good voltage clamping properties make the microchip bilayer method an excellent system to study the electrical properties of reconstituted membrane proteins simultaneously with optical probes.

Alkanes↗

Switching devices based on interlocked molecules.

An architectural rationale and an experimental program aimed at the development of molecular electronics switching devices for memory and computing applications are discussed. Two-terminal molecular switch tunnel junctions are identified as the critical device components of molecular electronics-based circuitry. They can be tiled in two dimensions and are tolerant of manufacturing defects. Singly and multiply configurable solid-state switching devices that are based upon electrochemically switchable molecular and supramolecular systems are discussed in terms of both the synthesis of the molecular components and the fabrication and performance of the devices.

Electrochemistry↗

Retention.

This article describes the mechanisms for retaining RPDs and considers the different types of direct retainer. The factors influencing the effectiveness of retentive clasps and governing the choice of clasp are discussed.

Dental Clasps↗

A system of design.

This article describes a method of building RPD components into an effective design and indicates how the details of the design can be communicated clearly to the dental technician.

Communication↗

Surveying.

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Dental Equipment↗

Communication between the dentist and the dental technician.

Factors contributing to good RPD design are described, including the respective inputs of the dentist and dental technician. Poor communication in current practice is reported and an appropriate format for a work authorization presented.

Communication↗

The removable partial denture equation.

This article describes the benefits and risks of providing RPDs. It emphasises the importance of co-operation between the dental team and patient to ensure that the balance of this 'equation' is in the patient's favour.

Dental Plaque↗