PubMed Health⌕ Search

Biomedical subjects

K Markiewicz

Publications and source records attributed to K Markiewicz.

At least 73 records · Page 4Linked to original sources
PubMed1982

[The behaviour of basal gastric secretion during exercise and restitution in chronic gastric and duodenal ulcer patients (author's transl)].

The behaviour of basal gastric secretion was examined in 15 gastric ulcer patients, 54 chronic duodenal ulcer patients, and 25 normal subjects. The investigation was conducted with the subjects remaining seated in three 1-hour phases at rest, during exercise, and in the course of restitution. The 60-minute exercise was performed on Monark's bicycle ergometer with loads producing constant heart rate acceleration ca 50% of the maximum for the subjects' age. The determination made included gastric juice volume, hydrochloric acid concentration and basal acid output (BAO) as well as sodium, potassium, chloride, calcium and magnesium levels in gastric juice. It was found that in healthy subjects a 1-hour exercise of constant 50% load significantly decreased the volume of gastric juice, concentration of hydrochloride acid and BAO as well as electrolyte content (rho less than 0.05): these changes were especially distinct during the restitution period. In the patients with gastric ulcer the basal gastric secretion presented a similar picture. By contrast, in the duodenal ulcer patients exercise produced increased volume of gastric juice and increased BAO values as well as higher electrolyte contents (rho less than 0.05). During the restitution period none of these values decreased below those determined at rest.

Adult↗
PubMed1982

[Influence of an ergometer load after intravenous lipofundin infusion on the behaviour of blood glucose, lactate, amino acid nitrogen and the free fatty acids (author's transl)].

In males aged from 19 to 21 years the influence of a bicycle ergometer load in the behaviour of blood glucose, lactate, amino acid nitrogen and the free fatty acids was examined. After determination of PWC120 20 subjects were loaded over 10 minutes in accordance with the value determined (group I). A second group (n = 15) was equally loaded after an intravenous infusion of 20-percent lipofundin. The subjects were given 2.5 ml per kg body weight (group II). The ergometer load of 10 minutes took place in the manner described above and was started 5 minutes after the end of the infusion. From the latter group 8 subjects (group III) were once again infused with lipofundin without subsequent physical stress. For determination of the parameters FFS, glucose, lactate and amino acid nitrogen venous blood was extracted at the time 0 minutes, immediately after the end of the lipofundin infusion of 20 minutes, after the end of the physical activity and 15, 30 and 60 minutes after the end of the ergometer load. The FFS rise was highest in group III, while in group II it was lower. During the load test the glucose concentrations rose in group I and were even during the reco very phase higher than in the two other groups. The amino acid nitrogen decrease in group II, but still more in group III. An increase took place in group I. The lactate rose in group II was significantly less than in group I (p less than 0.05). The results suggest a reduced utilization of glucose due to experimental increase of the FFS levels and a higher utilization of other energetic substrates.

Adult↗
PubMed1981

Effect of coffee ingestion on the left ventricular systolic time intervals at rest, during physical effort and the recovery period.

The investigations were carried out in 50 young healthy men, of whom 20 made an increasing submaximal physical effort on a bicycle ergometer after drinking a 250 ml coffee infusion (20 g of pure natural coffee); the remaining 30 men represented the control group. The left ventricular systolic time intervals (LVSTI) were obtained from polycardiograms by means of the Weissler et al. method. It was found that 20 minutes after coffee drinking the left ventricular ejection time index (LVETI) and LVET/PEP ratio increased whereas the pre-ejection period index (PEPI) and the isovolumic contraction time (ICT) decreased. This improvement of the activity of the heart as a pump which is indirect proof of increased myocardial contractility after drinking coffee was especially noticeable during subsequent phases of physical effort. The recovery period in group 1 was characterized by a reduced PEPI and ICT and increased LVETI and LVETI/PEP ratio as compared with the control group.

Adult↗
PubMed1980

The effect of maximal exertion on the levels of plasma peptides in cyclists with different physical working capacities.

The studies were carried out on thirty-one sportsmen, cyclists aged 21-28 years, after the termination of a training course just before the start of their season. They exercised on a bicycle ergometer according to the following schedule: 30 N at 60 rev/min for 6 min, 40 N at 70 rev/min for 5 min, 50 N at 80 rev/min for 5 min and 50 N at 90 rev/min until exhaustion. According to the level of training the subjects were divided into three groups. In the three groups of cyclists were determined the concentrations of total plasma peptides and their individual fractions obtained by gel-filtration on Sephadex G-10. It was found that the total plasma peptide concentration varied with the level of fitness. The lowest plasma peptide concentration was observed in cyclists with the lowest level of fitness and it differed from those observed in cyclists with intermediary and high levels of fitness. After exercise the biggest increase in plasma peptide concentration was found in the cyclists with the low level of fitness, and the lowest one in those with the high level of fitness. Individual plasma peptide fractions also revealed differences before and after exercise depending on the level of fitness.

Adult↗
PubMed1980

[Changes in blood biochemical parameters during physical exercise and recovery after prior diazepam administration].

The study involved 51 healthy males aged 20 -- 24, divided into two groups. Group I (30 subjects) performed exercise on a cycle ergometer with the load increasing according to the following schedule: 1 W/kg for six minutes, 2 W/kg -- six minutes, and 3 W/kg -- six minutes. The remaining 21 subjects (group II) performed identical exercise one hour after they had been administered 10 mg of diazepam (Relanium-Polfa). The determinations made included arterial blood levels of FFA, triglyceride, and glucose before the exercise, after each successive phase of the exercise, and in the course of restitution (30 minutes and 4 hours after the exercise). One hour after diazepam administration, the FFA, triglyceride and glucose levels decreased. After the successive phases of the exercise, the FFA levels were significantly lower among group II subjects, and continued to be so also in the 30th minute after the exercise. The decrease in the triglyceride levels during the exercise was higher among the diazepam subjects, and they were slightly lower also in the course of restitution. In both groups the glucose levels gradually increased after each phase of the exercise, and the increase after the third phase was higher among the diazepam subjects. During restitution the glucose concentration was higher than before the exercise, and slightly higher in group II.

Adult↗