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Biomedical subjects

L Hoffmann

Publications and source records attributed to L Hoffmann.

At least 163 records · Page 9Linked to original sources

[Digestibility and utilization of rations containing differently treated straw. 2. Energetic utilization by sheep of rations containing differently treated straw].

A total of 59 complete metabolic periods of adult sheep were used to compare energy balance and energy utilization of rations containing 45, 60 and 99% of straw previously subjected to different treatments. In addition, some indices of rumen physiology were determined. The straw was fed in the following forms: chopped, chopped and treated with 6% sodium hydroxide, pelleted with and without NPN-addition (ammonium bicarbonate and/or urea) during the pelleting process. Notwithstanding pressing temperatures above 90 degrees C during compaction, the addition of NPN-compounds did not result in increased digestibility. The NaOH-treatment of the straw increased the energy digestibility of the ration containing 45% straw by 5 to 6 digestibility units. All experiments revealed a higher energy balance and, consequently, a higher energy utilization than could be expected from calculations on the basis of equations derived from earlier experiments with adult sheep. The variations are discussed under the aspect of energetic feed evaluation and with regard to consequence for the efficient use of straw in rations for ruminants.

Animal Feed↗

[High-grade Urinary retention in the upper urinary tract due to ovarian cysts].

The obstructive uropathy of the upper urinary tract the reason of which is to be searched e.g. in congenital malformation, concrements hindering the passage, strictures and tumors of the urinary tract itself as well as in growing and displacing processes of the adjoining organs have often been observed and described. More seldom this is suitable for benign expansive processes of the ovary. Especially smaller growing and displacing benign processes in the ovary area may result in considerable difficulties concerning differential diagnosis. It is reported on a case of chronic urinary retention with cystic changes of the ovary.

Adult↗

[Energy requirements for the synthesis of body proteins during growth as determined in model experiments in rats. 2. Studies with dietary casein and wheat gluten used unsupplemented or supplemented with methionine or lysine].

Rats were used in 7 trials each comprising 9 animals (197 total metabolism trials carried out at an environmental temperature of 30 degree). The animals received casein, casein+methionine, wheat gluten, wheat gluten+lysine as protein sources and were investigated for their nitrogen and energy turnover. The rations fed contained between 10% and 27% protein. Supplementation of the natural proteins with synthetic amino acids positively influenced the growth rate and the rate of N retention. The feeding of wheat gluten as sole protein source induced an absolute depression of the food and energy intake. The rates of tetention of protein and fat energy per animal/day showed opposing trends, in dependence upon the protein levels in the rations. It was found in the trials with casein that the proteins yielded 25%, or 18% of the total energy retention if the rats received low protein rations while the percentage of protein energy retention increased to 49-53%, if the rations contained high protein levels. The rats utilized between 67% and 84% of the metabolizable energy for the turnover of body energy. A negative correlation was found between the levels of energy utilization and protein intake. The energy demends for protein retention were calculated (mean of all trials) to be 1.67 kcal of metabolizable energy while those for fat retention amounted to 1.15 kcal. The energy demands for protein retention were not found to be dependent on the type of protein source used. The maintenance requirements of the rats were 102 kcal of metabolizable energy per kg LM0,75.

Animal Feed↗

[Diagnostic strategy in diarrhea].

Planning the strategy in diagnosis of diarrhea some questions need to be answered: 1. Do the complaints in question fulfill the defined criteria of diarrhea? 2. Is it an acute diarrhea of infectious origin requiring fast microbiologic diagnosis? 3. Is it a chronic diarrhea? A) Do anamnestic findings and present status induce a certain suspected diagnosis, as in hyperthyreoidism, drugs, intestinal resections? B) Is a complete stepwise diagnostic planning needed as in Crohn's disease, insufficiency of the pancreas, non tropical sprue? Diagnostic measures have to be taken into consideration according to the answers given.

Body Water↗

[The effect of addition of formic acid to the rations on the energy metabolism of sheep and young bulls].

Total metabolism trials were carried out with 8 fattening bulls and 4 male sheep receiving rations supplemented with formic acid. Comparative trials were performed with lucerne conservates. The following results were obtained: Formic acid supplements of up to 0.7 gm/kg liveweight per animal/day did not influence the ruminal fermentation and the digestibility of the food beyond ordinary dissimilation processes nor did they influence the energy turnover in the animals. Already in the rumen, the added HCOOH was largely broken down into CO2 and CH4. Higher levels of N retention were observed if the animals were fed fresh lucerne silage supplemented with formic acid as compared with dried green feed and the other types of silage.

Animal Feed↗

[The estrogen dependence of the pregnancy associated alpha glycoprotein "SP3" and its occurrence in sera of patients with various malignant and benign diseases].

The pregnancy associated alpha-2-glycoprotein "SP3" is a macroprotein; the serum concentration of which is markedly enhanced by the increase of endogenous and exogenous estrogen. As regards the bronchial and uterine cancer the frequent presence of enhanced SP3 serum concentrations in tumour patients can be explained by an enhanced production of endogenous estrogen. This enhanced production has been described in literature. SP3 does not occur in healthy men and women without application of estrogen. In 26% of the cases it can be proved in cases of benign disease and in 52% in malignant cases having received no therapy of estrogen.

Contraceptives, Oral↗