Biomedical subjects
Publications and source records attributed to L M Gil-Carcedo.
This is a new method devised by the AA. in order to produce a laboratory experimental acoustic trauma, using a recorded noise. So it is possible to produce at will a noise strong enough to provoke a cochlear damage with the rythm, the frequency spectrum and duration chosen.
In the 25 day old guinea pig fetus the lateral wall of the ductus cochlearis is lined with a cylindrical epithelium consisting of a single layer of columnar cells, which opens onto the endolymphatic space. It is clearly separated from the adjacent structures by a basal membrane. This connective tissue contains numerous cells with fibroblastic features, more abundant and larger, the nearer they are to the basal membrane. In the segment of the marginal cells adjoining the endolymphatic cleft sometimes shows up a basal body, suggesting the existence of a kinocilium. The cellular surface is covered with small microvilli. In the 50 day old guinea pig fetus, the development of the stria vascularis is already similar to that of the adult animal.
A three-year-old girl with hypertelorism suffered seven episodes of meningitis. X-ray, CT scan and gamma-cisternography revealed a meningoencephalocele at the base of the skull. At operation, a 'hole' of about 25mm was clearly visible in the midline, just behind the lamina cribrosa; through this a piece of brain tissue protruded towards the nasal cavities. The herniated brain-tissue was removed and the gap was closed. Meningitis did not recur.
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Two cases of monostotic fibrous dysplasia of the ethmoid are presented. This condition is of interest to the rhinologist because of the difficulty of differential diagnosis, its location, and the frequent tendency to local recurrence. The two patients presented in this paper were aged fifteen and seven respectively, with almost identical lesions and with very similar x-rays. A clinical picture of each patient is given, following a brief description of fibrous dysplasia. Special emphasis has been placed on the treatment which is necessarily surgical. In both cases extensive radical surgery of the lesion was performed using a combined craniofacial approach. Finally, a brief evaluation is made of these two cases.
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Two cases are reported of intracranial complications of sinusitis, unusual nowadays. They were caused by osteomyelitis of the frontal bone following chronic frontal sinusitis. These cases were distinguished by complete destruction of the posterior wall of the sinus involved: in one of the cases there was an acute central neurological disturbance caused by a cerebral abscess; in the other patient, who came for consultation because of a Pott's Puffy tumour, a sizeable epidural abscess was found.
A case is presented of anhidrotic ectodermal dysplasia, of extreme rarity. This is distinguished by disorders in the structures of ectodermal origin. The clinical characteristics--hypohidrosis, hypodontia, hypotrichosis-, and the genetic features--genealogy, karyotype--are examined first. The patient's face appears to be small, due to the combination of frontal bossing, hypodontia, and a depressed nasal dorsum, somewhat resembling the saddle nose of congenital syphilis. The case is studied from various perspectives: clinical, radiological, anatomicopathological and ultrastructural. The study concentrates principally on the anomalies of the nasal cavities, where there is a notable atrophy of the nasal mucosa. This atrophic rhinitis displays all the features of ozaena: severe crusting, fetid green secretion, nasal obstruction, etc.
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