Coronary Angioplasty of a Single Coronary Artery with an Anomalous Origin in the Ascending Aorta.
Explore the source record for details and available documents.
Journal Article↗
Biomedical subjects
M Fu
Publications and source records attributed to M Fu.
[Optimization of technical parameters for processing radix Aconiti coreani].
Based on the determination of guanfu A, hypaconitine, and total alkaloids, along with the experiment of acute toxicity of sliced Radix Aconiti Coreani and in compliance with the quality standard stipulated in pharmacopeia-surface features cross section colour and odor of sliced Radix Aconiti Co-reani the technology of processing Radix Aconiti Coreani has been optimized to be steaming the drug for four hours.
Aconitine↗
[Influence of processing on the content of hypaconitine in the roots of Aconitnum coreanum (Lévl.) Rapaics].
In this paper, the contents of hypaconitine in the roots of Aconitum coreanum and its processed products were determined by high performance liquid chromatography. The result provides scientific basis for processing the roots of Aconitum coreanum.
Aconitine↗
[Orthodontic treatment in unilateral cleft lip and palate patients with crossbite].
Serious malocclusion is often seen in the cleft lip and palate patients. Orthodontic treatment is very complex and difficult. The aim of this study was to investigate the characteristics of the treatment in this kind of the patients through the clinical treatment of the thirty-two patients. We conclude (1) Many patients need alveolar bone grafting in order to award good arch form and occlusion. (2) It need longer time in expanding of the upper arch and retaining. (3) Main changes after treatment of edgewise appliance took place in dental-alveolar region. (4) 34.3% of the patients need orthognathic surgery to improve their profile. So it indicated that reverse headgear should be used in the early time for the cleft patients to get a good treatment result.
Adolescent↗
[Effect of skeletal Class III malocclusion on speech articulation].
The purpose of this study was to investigate the effects of skeletal class III malocclusion on speech articulation. The subject was twenty skeletal class III malocclusion adults. Their articulations were evaluated by phoneticians and the disordered speech sounds were analysed by computerized speech lab. It was manifested that most of the adults had misarticulations, the most common speech sound errors were consonants (zh, ch, sh, z) and the types of errors were distortion and substitution. Compared with the normal consonants acoustic analysis of the disordered ones showed that, the lower boundary frequency got down, spectrum distribution in frequency became widen, as well as the lower frequency components were enhanced. The results suggested that skeletal class III malocclusion may cause deficiency in speech production. The improvement of speech articulation should be considered when the severe skeletal discrepancy was corrected by surgical-orthodontic treatment.
Adolescent↗
Percutaneous transluminal angioplasty of the right coronary artery having an anomalous origin: two cases report.
Percutaneous transluminal coronary angioplasty was performed on 2 patients, each having an anomalous origin of the right coronary artery with anterior-superior orientation. Each patient had experienced post-infarction angina after an inferior wall myocardial infarction without antecedent thrombolytic therapy. The procedures were successfully performed with appropriate selection and manipulation of the guiding catheter. Our findings indicate that the Amplatz left catheter is the guiding catheter of choice in catheterizing a right coronary artery of anomalous origin with anterior-superior orientation.
Aged↗
Utility of 10 MHz ultrasound catheters in the intraaortic assessment of coronary artery ostial stenoses.
Our preliminary observations show that intraaortic intravascular ultrasound using 10 MHz transducer catheters is safe and feasible in the assessment of coronary ostial lesions. This imaging modality is potentially useful in decision making regarding the choice of coronary intervention.
Aged↗
Modulation of brain catecholamine absorbing proteins by dopaminergic agents.
Catecholamine absorbing proteins (CATNAPs) are localized in the brain and thus far have no known biochemical and pharmacological characteristics consistent with other receptor proteins or metabolic enzymes in the central nervous system. The oxidative metabolism of catecholamines in the brain, especially the catabolism of dopamine and its conjugation with metabolic brain proteins, results in the production of highly toxic free radicals. Since such processes are implicated in the pathophysiology of various neurodegenerative diseases, including parkinsonism, and since CATNAPs bind catecholamines with high affinity, there is a need to further investigate if these novel proteins could play a protective role against these harmful catecholamine metabolites. In this study, we demonstrate the purification, pharmacological characterization and modulation of CATNAPs, as the first steps necessary to elucidate the function of these proteins in the brain. First, CATNAPs were identified from tissues using [3H]N-n-propylnorapomorphine (a specific dopamine receptor agonist) and [125I]6-hydroxy-5-iodo[N(N-2,4-dinitro-phenyl)- aminopropyl]1,2,3,4-tetrahydronaphthalene ([125I]DATN; a highly specific ligand synthesized in our laboratory). Three proteins, with molecular masses of 47, 40 and 26 kDa, were identified and purified, which allowed for the subsequent production of antibodies against each of these CATNAPs. The effects of in vivo chronic administration of several dopaminergic agents on CATNAPs were also examined by Western immunoblotting. L-3,4-Dihydroxyphenylalanine (L-DOPA) treatment in rats resulted in the increase of all of the three proteins, as compared to controls. Treatment in rats with the dopamine depleting agent, reserpine, produced a significant decrease in all of the three CATNAPs. In addition, the effects of direct administration of apomorphine, dopamine, epinephrine, isopropylnorepinephrine, norepinephrine, N-n-propylnorapomorphine and 6-hydroxydopamine on CATNAP levels in rats were examined. Interestingly, we observed an increase (as compared to control) of the 47, 40 and 26 kDa proteins in animals treated with dopamine, norepinephrine, N-n-propylnorapomorphine and apomorphine. In contrast, animals treated with 6-hydroxydopamine showed significant decreases in the levels of all three proteins. It is evident that as the concentration of catecholamines increases, there is a corresponding increase in the levels of CATNAPs in the brain. These results clearly demonstrate the pharmacological modulation of CATNAPs by dopaminergic agents and suggest their possible role in the cytoprotection against damage caused by free radicals generated by oxidative stress.
Adrenergic Uptake Inhibitors↗
Characteristic distribution of circulating autoantibodies against G-protein coupled cardiovascular receptors in patients with idiopathic dilated and hypertrophic cardiomyopathy.
Circulating autoantibodies against cardiovascular membrane receptors have been repeatedly demonstrated in a subgroup of sera of patients with idiopathic dilated cardiomyopathy. This short review summarizes the clinical findings on anti-receptor autoantibodies in patients with dilated cardiomyopathy.
Autoantibodies↗
Learning multiple causes by competition enhanced least mean square error reconstruction.
In this paper we studied a self-organization principle that input should be best reconstructed from a factorial distributed hidden representation, which has been addressed in the literature recently. An auto-encoder network is trained by the Least Mean Square Error Reconstruction (LMSER) while the redundance in the representation is reduced by a proposed anti-Hebbian scheme, in which a penalty term called Receptive Field Overlapping Index (RFOI) is combined into the objective function for enhancing competition among nodes in the network. Our learning scheme provides a way for balancing the cooperation and competition necessary for the self-organization process thus realizes the multiple causes model, which accounts for an observed data by combining assertions from the discovered causes or features in the data. Our experiment results demonstrate again the powerful information processing capability inherent to the popular weighted sum followed by sigmoid squashing. Comparing with previous probability theory based multiple causes models, our scheme is much easier to implement and quite reliable.
Algorithms↗
Percutaneous transvenous mitral commissurotomy in patients with mitral stenosis and coexistent hyperthyroidism.
Percutaneous transvenous mitral commissurotomy (PTMC) was performed successfully without complications in 3 patients with severe mitral stenosis and hyperthyroidism. All 3 patients had pliable, noncalcified mitral valves. One patient who had been treated with methimazole for 6 months was still in a hyperthyroid state when she presented with intractable congestive heart failure and was found to have severe mitral stenosis. The heart failure improved immediately after PTMC, but the patient remained in New York Heart Association functional class 2 until a euthyroid state was achieved with I131 therapy. In the other 2 patients, hyperthyroidism was unsuspected at the time of PTMC. Unexpectedly suboptimal symptom improvement led to the diagnosis of hyperthyroidism 1 month after the intervention. In all 3 patients, PTMC resulted in an immediate hemodynamic and clinical improvement. However, complete clinical improvement occurred only when euthyroid state was achieved after antithyroid treatment. The present study suggests that PTMC is a safe and effective intervention modality in patients with coexisting hyperthyroidism and severe mitral stenosis. The procedure may be considered a therapeutic option in patients with hyperthyroidism and severe mitral stenosis.
Adult↗
Usefulness of intracardiac echocardiography in complex transseptal catheterization during percutaneous transvenous mitral commissurotomy.
OBJECTIVE: To examine the utility of intracardiac echocardiography in guiding complex transseptal catheterization of patients undergoing percutaneous transvenous mitral commissurotomy. DESIGN: We assessed this procedure in high-risk patients in whom transseptal catheterization is technically complex and more demanding. MATERIAL AND METHODS: Fifteen patients with mitral stenosis were studied. Twelve patients had giant left atria (70 mm or more), two had atrial septal aneurysms, and one had severe kyphoscoliosis. A newly developed 8-F 10-MHz intracardiac transducer catheter was placed in the right atrium through an 8-F Mullins sheath inserted from the left femoral vein. Echocardiographic images were used to confirm the septal position of the Brockenbrough needle tip before septal punctures. RESULTS: Transseptal puncture was successful and uncomplicated in all 15 patients. Use of intracardiac echocardiography eliminated the need for atrial angiography. Before transseptal puncture, the needle tip was identified to be in contact with the atrial septum, as an echogenic point with its acoustic shadow and septal indentation. In addition, in the two patients with aneurysms, puncture of the thin-walled aneurysms was avoided. CONCLUSION: Intracardiac echocardiography facilitates safe complex transseptal catheterization in patients with mitral stenosis and giant left atria, atrial septal aneurysms, or severe kyphoscoliosis.
Cardiac Catheterization↗
Partially unroofed coronary sinus and persistent left superior vena cava: intracardiac echocardiographic observation.
Unroofed coronary sinus, a rare congenital anomaly first described by Raghib and colleagues1 in 1965, is a result of an embryologic error involving imperfect or complete failure of development of the left atriovenous fold, which is manifested as a focal (fenestration or partial unroofing of the coronary sinus) or complete absence of the coronary sinus septum. Before the era of echocardiography, precise diagnosis of this anomaly was possible only during surgical procedure or at autopsy. Since the advent of the echocardiography, several studies have reported the usefulness of two-dimensional transthoracic and transesophageal echocardiography in the diagnosis of unroofed coronary sinus. We describe the intracardiac echocardiographic delineation of partially unroofed coronary sinus and persistent left superior vena cava in a patient with atrioventricular nodal reentrant tachycardia. Incidental finding of the dilated coronary sinus during radio frequency ablation of the tachycardia led to the diagnosis of this unusual anomaly.
Adult↗
Anomalous origin of left coronary artery from right coronary artery (single coronary artery): diagnosis by transesophageal echocardiography.
Explore the source record for details and available documents.
Coronary Vessel Anomalies↗
[Assignment of differentiation-relevant cDNA RA538 on human chromosomes by fluorescence in situ hybridization].
OBJECTIVE: To localize the differentiation-relevant cDNA RA538 (3.8kb) onto the human chromosome 8q2. METHODS: A modified non-isotopic labeling technique was used. RESULTS: The cDNA RA538 was obtained by subtraction hybridization from human esophageal cancer cell line EC8712 induced by retinoic acid. Fluorescence in situ hybridization (FISH) using double-labeled probes showed clear and paired hybridization signals at the corresponding regions of both two chromatids in 18 out of 60 metaphases examined. While by single-labeling, only 7 were positive in 60 metaphases observed and the fluorescent spots were seen only at one chromatid. CONCLUSION: The modified FISH protocol is useful for mapping cDNA sequences of a few kilobases.
Antineoplastic Agents↗
Malignant fibrous histiocytoma of the left ventricle: a case report.
Malignant fibrous histiocytoma (MFH) is the most common soft tissue sarcoma in adults, but is distinctly rare as a primary tumor of the heart. Herein we report a case of left ventricular MFH obstructing the outflow tract and presenting as congestive heart failure. Surgical removal of the mass confirmed the tissue diagnosis of MFH. To our knowledge, this is the first report of MFH originating from the left ventricle.
Aged↗
[Antitussive, expectorant and anti-inflammatory effects of rhizoma Cynanchi stauntonii].
Experiments indicated that the ethanol extract and ether extract from Rhizoma Cynanchi Stauntonii showed obvious antitussive and expectorant effects in mice with stomach administration. The antitussive effect of ethanol extract was stronger than the expectorant effect. The water extract showed a certain expectorant effect but no marked antitussive effect with oral administration. Obvious anti-inflammatory effect was observed on croton oil-caused mouse ear swell with intraperitoneal injection.
Animals↗
[Comparison of diet, physical activity and serum lipids between Chinese and Japanese: Chengdu-Fukuoka Study].
A detailed diet history was taken from 326 Chinese adults, 116 college students in Chengdu, China, and 300 Japanese adults and 4529 college students in Fukuoka, Japan. Both populations consume high carbohydrate and low fat diet, but the Chinese diet was higher in carbohydrate, cereal energy/total energy ratio and polyunsaturated fatty acids/saturated fatty acids ratio, and lower in protein, fat and animal fat/total fat ratio compared to the Japanese diet. Cholesterol intake was significantly lower in Chinese than in Japanese (P < 0.001). Physical activity index in Chinese was higher than that in Japanese. Serum lipids and lipoprotein cholesterols were measured in the adults of Chinese and Japanese. Except the serum triglycerids level in female, the total cholesterol, TG, high density lipoprotein-cholesterol and low density lipoprotein-cholesterol levels in Chinese adults were lower than those in Japanese adults (P < 0.001). Since cholesterol is the major predisposing factor for coronary heart disease and the results of our study show that a high carbohydrate and low fat diet can be effective in lowering the cholesterol level in blood it will be of interest to see which kind of oriental dietary may be a preventive against coronary heart disease.
Adult↗