PubMed Health⌕ Search

Biomedical subjects

M Pollock

Publications and source records attributed to M Pollock.

At least 91 records · Page 5Linked to original sources
PubMed1976

Combined therapy with tetrabenazine and pimozide in Huntington's chorea: pilot study.

Current medication for Huntingtons chorea is based on compounds which affect the activity of acetylcholine and dopamine in the basal ganglia and is unsatisfactory. This report describes a small clinical trial of dopamine antagonists, tetrabenazine (Nitoman) and pimozide (Orap). Improvement was early and striking but was not maintained over the trial period of 83 weeks.

Adult↗
PubMed1976

Peripheral nerve morphometry in myotonic dystrophy.

Biopsy specimens of muscle and cutaneous branches of the common peroneal nerve from four patients with myotonic dystrophy (MD) were evaluated by morphometric techniques and compared to age-matched control nerves. Myelinated fiber densities were normal in the superficial and deep peroneal nerves of patients with MD. Internode length and frequency of abnormal fibers was not significantly different in MD and control nerves, nor were the number of myelin lamellae, number of neurofilaments per unit area, or number of microtubules per unit area to axis cylinder area. There was no evidence of morphologic abnormality of peripheral nerve in MD.

Adult↗
PubMed1970

Isolation of L-forms of Bacillus subtilis which grow in liquid medium.

L-forms of Bacillus subtilis can be isolated by treatment of the parent strain sequentially with N-methyl-N'-nitro-N-nitrosoguanidine and lysozyme and selection of the surviving protoplasts on semisolid medium containing 2,000 units of penicillin per ml. Some of these clones can be adapted to grow in liquid cultures containing 1.2 m NaCl. This method will aid in the isolation of cell wall mutants which require hypertonic medium for growth.

Bacillus subtilis↗