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N Tsuji

Publications and source records attributed to N Tsuji.

At least 127 records · Page 7Linked to original sources
PubMed1987

Study of the selectivity of the impregnation of neurons by the Golgi method.

The selectivity of the impregnation of neurons by the Golgi method was examined by comparing Nissl-stained specimens with Golgi-stained specimens in terms of the somatic orientation, cross-sectional area, and long and short axes of the soma in the ventromedial hypothalamic nucleus (VMH) and lateral hypothalamic area (LHA) of 5-week-old rats. With regard to somatic orientation, we made comparisons directly between the Nissl distribution pattern and the Golgi pattern. The two distribution patterns did not differ significantly in either VMH or LHA (Smirnov test, P greater than 0.05). For somatic cross-sectional area and diameter (long and short), a mean value of every 10% of the total frequency was estimated for each histogram; the histogram was segmented into 10 percentile frequency domains, and a mean value for each domain was estimated. A linear regression was calculated between Golgi mean values and Nissl's at the same place. By use of the linear regression, all of the observed values on Nissl sections for somatic cross-sectional area and diameter were transformed into their corresponding Golgi values. The frequency distribution of these transformed Nissl values was compared with that of the actually observed Golgi values. There was a high degree of similarity between the two distribution patterns in all regions examined for long and short diameters as well as cross-sectional area of the soma (Smirnov test, P greater than 0.05). These findings suggest that the sampling of VMH and LHA neurons in the Golgi method used in the present study is similar to the corresponding sampling in Nissl preparation.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗
PubMed1987

Syndrome of microcephaly, deafness/malformed ears, mental retardation and peculiar facies in a mother and son.

We report a mother and son who have a microcephaly with a characteristic dysmorphic face. Prominent manifestations include facial asymmetry, prominent glabella, deafness, low-set, cup-shaped ears, thick, protruding lower lip, micrognathia, and mental retardation. We conclude that these patients have a previously undescribed type of genetic microcephaly. The mother has become normocephalic and we would not have been able to diagnose her condition without her childhood photographs. Such photographs are essential in the recognition of familial syndromes.

Abnormalities, Multiple↗
PubMed1987

[Spinal epidural abscess--report of 5 cases].

We reported 5 patients with spinal epidural abscess. They were two men and three women. Their ages ranged from 48 to 56 years (mean, 53 years). In three out of 5 cases, the etiology was thought to be infection after lumbar discography, tracheostomy and lumber surgery. In the other two cases the etiology could not be determined. The abscess was located at cervical, thoracic and lumbar levels in 2, 1 and 2 cases, respectively. The interval between initial symptoms and operation was from 1 to 3 months. Purulent epidural collection was found in four cases at operation. Irrigation and drainage were sufficiently performed postoperatively in 4 cases. Antibiotic therapy had been continued for at least 8 weeks in every case. As demonstrated in the case 2, CT scan was very useful in determining the extension of the abscess and degree of the cord compression by the abscess. Also in the case 2, the epidural abscess extending from cervical canal to extracanalicular space was completely drained by applying draining tubes without laminectomy. The present results indicate that emergency laminectomy is not always necessary for the treatment of epidural abscess, especially in subacute or chronic cases.

Abscess↗
PubMed1987

[Surgical treatment of the herniated cervical disc--a consideration on the choice of operative method following our experience with 200 patients].

There is a controversy on the surgical treatment for the so-called cervical herniated disc. Recently operators choosing the anterior approach have increased in more and more. However, considering the historical view of the treatment of disc disease, it is obvious that the posterior approach is also an important method, especially in the cases combined with the stenotic cervical spinal canal. During the past five years 200 patients of cervical herniated disc disease were operated in our clinic by using our newly devised instruments and new materials. We studied the relation between the operative approach, the extent of interbody fusion and the surgical results. The social adaptation of the operated patients was also examined especially by comparing the short follow-up with the long one. Regardless of surgical approach, the percentage of the good recovery is higher (10% at the most) in the short follow-up than that in the long observation. The consequence is thought to show that the social adaptation deteriorates as the time goes on. Based on these results, the historical aspects and the technical problems of anterior and posterior approach were reviewed, focusing especially the controversial points. On the other hand, presenting our opinion on the surgical approach, we showed how the surgical problems have been solved and other complications lowered by introducing our new technique. Consequently, we stress that it is insignificant to discuss whether we should choose the anterior approach or the posterior approach. Finally, in case of criticizing the surgical results, it is reemphasized that we should think over not only the simple operative results, but also the aspect of social adaptation.

Adult↗
PubMed1986

Extradural multiple spinal meningioma. Literature review a case report.

A case is reported of recurring or multiple spinal meningioma and focuses again on the incomplete information at present available regarding this class of meningioma. Repeated operations were performed earlier in the extradural space at C2 and an intradural tumour at the same level was completely removed. After a six year interval, we diagnosed an intramedullary meningioma once again at C2, which was subtotally removed. Histological examination indicated an angioblastic tumour, the same type of meningioma as was previously found. Postoperative recovery was satisfactory. Two years later, an intradural extramedullary tumour at T2-3 level was totally removed. Again postoperative recovery went well. In view of the rare occurrence of this meningioma, and the reports on it, we envisaged the pathogenesis of our case as an invasion from the extradural into the intradural space and into the spinal cord. Its appearance in the thoracic region might have been by dissemination via the cerebrospinal fluid pathways or it may have occurred independently.

Humans↗
PubMed1985

Morphometry of cytoarchitecture of the lateral hypothalamic area in the rat.

The cytoarchitecture of the lateral hypothalamic area (LHA) in rats was studied with cresyl violet-stained coronal celloidin sections and with sections of the brain impregnated by a Golgi method. Unimodality was established in the frequency distribution histogram of both the somatic cross-sectional area of the LHA neurons and somatic shape (elongation and circularity). The predominant somatic orientation was in the dorsomedial-ventrolateral direction: bimodality of the frequency distribution of somatic orientation was denied. These findings suggest that the LHA neurons examined in the present study are not subdivisible on the basis of the somatic area, shape or orientation. Although the neurons were classified into eight types based upon the dendritic pattern, those in the LHA largely consisted of only three of them; Type III (dendrites extending in two directions along the long axis of soma), Type IV (three directions) and Type VIII (four directions) jointly accounted for 97.1 percent of the total neurons examined. This finding suggests that the parameter of dendritic pattern serves an important purpose in the typing of the rat LHA neurons. The orientation of intrinsic dendrites and intrinsic axons in the LHA has also been described.

Animals↗
PubMed1984

Moyamoya disease associated with craniopharyngioma.

A case of coexisting moyamoya disease and craniopharyngioma in an 8-year-old boy is reported. The patient had been suffering from recurrence of transient right hemiparesis with headache and vomiting during the three years before admission. After the diagnosis of both moyamoya disease and craniopharyngioma, evacuation of the cystic fluid of the craniopharyngioma, encephalomyosynangiosis , and internal irradiation through an Ommaya drainage system were carried out. The symptoms gradually improved after these procedures. The relation of moyamoya disease to craniopharyngioma is discussed. We consider that internal irradiation is one of the best means of treatment for a cystic craniopharyngioma associated with moyamoya disease.

Arterial Occlusive Diseases↗
PubMed1981

Cranial chondromyxoid fibroma. Case report.

A case of chondromyxoid fibroma of the frontal bone in a 15-year-old girl is presented. This is a benign tumor, but should be excised widely enough to include a rim of normal bone, otherwise it may recur or even undergo malignant transformation.

Adolescent↗