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Biomedical subjects

R Hoigné

Publications and source records attributed to R Hoigné.

At least 73 records · Page 4Linked to original sources
PubMed1975

[Side effects of antibiotics].

The clinically severe and newer forms of antibiotic side effects are reviewed. The study covers the following antibiotics: penicillins, cephalosporins, aminoglycosides and polymyxins, tetracyclines, chloramphenicol and thiamphenicol, macrolides and lincomycin, rifamycins and sulfonamides. Special reference is made to (1) hematologic side effects, and (2) general evaluation of drug reactions. The relationship between reaction time and clinical symptoms is of particular practical significance.

Anaphylaxis↗
PubMed1975

[Neurologic aspects of cranial arteritis].

This study describes 44 cases of cranial arteritis (41 of whome had been established by arterial biopsy). Special attention has been payed to the type and the significance of initial symptoms. The majority of the patients were from 65-80 years, the youngest 55 years old. The frequency was slightly higher in the male than in the female. All the patients except for two suffered from pain in the area of the head or the face. Ocular disorders had been found in 62% of the cases, commonly represented by blindness of one eye, decreased vision, papillar edema and eventually by occlusion of the retineal artery. The sedimentation rate of red blood cells showed acceleration between 32 and 130 mm after 1 hour. In the average a laps of time of one month was noted between the appearance of the first subjective symptoms and the moment when diagnosis was made. The administration of 60-80 mg Prednisone daily was followed by a decrease in the clinical signs within a few days to 3 weeks. It is important that therapy be started with a high dosis of Prednisone and that it should be reduced to smaller doses given during several years.

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