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R J Craig

Publications and source records attributed to R J Craig.

At least 37 records · Page 2Linked to original sources

16 PF profiles and typologies for patients seen in marital therapy.

The purpose of this study was to examine and describe the personality characteristics of 145 patients seen in outpatient marital therapy in private practice. Cluster analysis of the entire sample resulted in five separate typologies which were statistically significant and clinically meaningful and which suggested different goals for counseling. Patients seeking marital therapy were significantly more tense, anxious, worrisome, suspicious, bold, and shrewd than the normal persons in the 16 PF standardization sample.

Adult↗

Psychological screening of impotence with Finney's MMPI-derived Impotence Scale.

Three groups of patients in treatment were assessed for impotence, using MMPI-derived Impotence Scale. Group I were 46 patients who had been screened and scheduled for a penile prosthesis when the impotence resulted from known organic causes (biogenic). Group II were 198 patients in a sexual dysfunction clinic, for whom biogenic causes had been ruled out (psychogenic). Group III were 51 substance abusers in drug rehabilitation. While scores on the Impotence Scale did not distinguish between the biogenic and psychogenic groups, the scores were almost three times higher than average scores among subjects in the standardization sample. MMPI-derived Impotence Scale scores were similarly elevated among the substance abusers. Results suggest that the Impotence Scale may serve as a useful screening tool to alert clinicians to the possibility of erectile dysfunction for which further clinical evaluation would be required.

Adult↗

Psychological screening of sexually violent offenders with the MCMI.

The MCMI was administered to 603 recently convicted violent offenders, grouped according to nature of the offense into child molesters (n = 201), rapists (n = 195), and non-sexually aggressive felons (n = 205). Both groups of sexual offenders were more passive-aggressive, but child molesters were more dependent, anxious, and depressed than the other two groups, whose personality style was more narcissistic and independent with little psychic distress. Results confirm earlier findings based on MMPI test results, which show that the personality styles of rapists are more similar to those of non-sexually aggressive felons than to those of child molesters. Test variance can no longer be the basis for these replicated findings.

Adult↗

Structural organization of the genes encoding human and murine FK506-binding protein (FKBP) 13 and comparison to FKBP1.

FK506-binding protein (FKBP)12 and FKBP13 are members of a family of proteins which bind the immunosuppressant drugs, FK506 and rapamycin. FKBP12 and FKBP13 are encoded by distinct genes, designated FKBP1 and FKBP2, respectively. The structure of human FKBP1 was previously characterized. We now report the genomic structure of the human and murine FKBP2 genes. Comparison of FKBP1 and FKBP2 reveals significant homology and correlation of intron positions in the C-terminal region, suggesting that these genes may have evolved from a common ancestral gene.

Amino Acid Sequence↗

Chromosomal band assignments of the genes encoding human FKBP12 and FKBP13.

Human FKBP12 and FKBP13 are encoded by distinct genes designated FKBP1 and FKBP2, respectively. Human FKBP1 was previously characterized. The characterization of human FKBP2 is described. FKBP2 is three kb in length and contains six exons. Fluorescence in situ hybridization of FKBP1 and FKBP2 genomic probes to metaphase chromosomes localized FKBP1 to human chromosome 20 band p13 and FKBP2 to human chromosome 11 band q13.1-q13.3.

Amino Acid Sequence↗

Assessing drug abusers with the Millon Clinical Multiaxial Inventory: a review.

This paper reviews studies that used the Millon Clinical Multiaxial Inventory with drug abusers. Although the test has been used with over 2000 such patients in the published literature, there is still a dearth of basic research with the MCMI with this population. Preliminary evidence suggests that the Personality Disorder Scales are quite useful to assess personality styles of drug abusers, but the Clinical Syndrome Scales present some problems. Specifically, the Drug Dependence Scale has had difficulty in reliably "detecting" drug addicted individuals who were in treatment for drug abuse. However, a reliable modal MCMI profile among this population seems to exist, although cluster research suggests several subtypes, each with different personality styles. MCMI computer-narrative reports may overdiagnose paranoid disorder and under diagnose antisocial disorders among this population.

Humans↗

Personality factors in Psy.D. students: empirically derived comparisons between men and women.

A total of 180 students in a Doctor of Psychology program of an APA-accredited Professional School of Psychology (55 men and 125 women) took the MMPI for course requirements. A larger subgroup (43 men and 88 women) also completed the Adjective Check List. Men scored higher than women on the MMPI dimensions of Assertion (Pd), Organization (Pt), and Imagination (Sc). Women scored higher on the Ego Strength Scale (Es). Men scored higher on the Check List scale of Dominance. Data were compared with a previous report of MMPIs of Ph.D. students, and few differences were observed. Findings were discussed in terms of stereotypical role behaviors from which doctoral students are not yet immune.

Adult↗

Relationship between MCMI-II scales and normal personality traits.

We correlated MCMI-II and 16 PF profiles of 145 couples in outpatient marital therapy and noted significant associations between these tests that were consistently and logically related to constructs which underlie the meaning of the MCMI-II scales. This provided good concurrent validity for both the Personality and Clinical Scales of the MCMI-II. These results add credence to research designed to study Millon's basic styles in normal populations.

Adult↗

MMPI subtypes for cocaine abusers.

The MMPIs of 104 cocaine abusers in treatment were subjected to a hierarchical cluster analysis and two basic profile types emerged. Type I consisted of a spike on Pd and a subspike on Hyp, reflecting a rebellious, acting out character-disordered style with narcissistic traits. Type II consisted of a high-ranging, floating profile consisting of marked elevations on F, Sc, Dep, Pt, Pd, and Pa, reflecting a psychiatric patient who concurrently abused cocaine. These findings were contrasted to other MMPI typological studies, and the similarities and differences were discussed.

Adult↗

Conscious and unconscious perceptions of self in children of alcoholics.

The conscious and unconscious self-concept was examined in three groups of children: 23 children of alcoholics (COA), 19 children from nonalcoholic but dysfunctional families, and 23 children from normal families without alcoholism or family dysfunction. Self-concept was assessed both objectively, using the Piers-Harris Children's Self Concept Scale, and subjectively, using the Draw-A-Person Test and the Thematic Apperception Test from rating systems designed to tap unconscious dimensions of self. The COAs and normal controls were also compared for behavioral problems with the Achenbach Child Behavior Checklist. We found that COAs made more positive self-statements on objective measures of self-concept than children from families without alcoholism, whether or not the families were dysfunctional. Subjective analyses of projective test responses revealed unconscious differences in self-concept among the COAs, though this was not corroborated with objective scores, probably due to the crudeness of the rating instrument in failing to tap these dimensions. Also COAs had significantly more behavior problems, based on parental reports, which contrasts with their objective reports of self. Implications of these findings were discussed.

Alcoholism↗

Exon organization of the human FKBP-12 gene: correlation with structural and functional protein domains.

FKBP-12, the major T-cell binding protein for the immunosuppressive agents FK506 and rapamycin, catalyzes the interconversion of the cis and trans rotamers of the peptidyl-prolyl amide bond of peptide and protein substrates. The function of rotamase activity in cells and the role of FKBP-12 in immunoregulation is uncertain. In this paper we report the cloning and characterization of the human chromosomal FKBP-12 gene and four processed FKBP-12 pseudogenes. The FKBP-12 gene is 24 kilobases in length and contains five exons. The protein-coding region of the gene is divided into four exon modules that correlate with the structural and functional domains of the protein. The novel structure of FKBP-12 resulting from the topology of the antiparallel beta-sheet is the topological crossing of two loops that are encoded by separate exons. Separate exons also encode the antiparallel beta-sheet and alpha-helical region that define the drug-binding pocket and enzyme activity site of FKBP-12. The exon organization of the FKBP-12 gene also provided insight into the genetic evolution of the immunophilin family. Knowledge of the FKBP-12 gene structure will enable inactivation of this gene by homologous recombination in cells to provide a model to study the role of FKBP-12 in immunoregulation and normal cellular processes.

Amino Acid Sequence↗

Relationship between Wechsler scales and Peabody Picture Vocabulary Test-Revised scores among disability applicants.

Relationships, including age, race, gender, and IQ level, between the Wechsler intelligence scales (WISC-R, WAIS-R) and the Peabody Picture Vocabulary Test-Revised (PPVT-R) were studied among 206 applicants for disability benefits in a private practice setting. We found that the PPVT-R seriously underestimated WISC-R IQs by an average of 5 points and WAIS-R IQs by an average of 12 points. Results were discussed in terms of psychometric findings and clinical application. The study demonstrates that psychologists in private practice settings can use the product of their daily work to address important questions that require empirical answers, which, in turn, can influence clinical practice.

Adolescent↗

MCMI comparisons of cocaine abusers and heroin addicts.

Cocaine addicts (N = 107) and opiate addicts (N = 86) in treatment for drug abuse were compared on the MCMI. Univariate analyses revealed that cocaine abusers showed more traits of the antisocial personality style, whereas heroin addicts evinced more problems with anxiety and somatic distress, probably related to residual problems of withdrawal, and alcohol abuse. Multivariate analyses revealed four distinct clusters (MCMI patterns 456', 865', 56', and 8') that aligned by underlying personality style and clinical syndrome expression rather than by drug of choice. Ideographic analyses further demonstrated consistencies in prevalence rates of DSM-III-R personality disorders. Results do not support the pharmacodynamic theory of drug abuse. It was concluded that the similarities in personality between these two groups are greater than their differences.

Adaptation, Psychological↗

Mental representations of physically and sexually abused latency-aged females.

The mental representations and self-concept of 20 sexually abused, 20 physically abused, and 20 nonabused but distressed females, ages 7-12, were studied using the TAT and the Piers-Harris Children's Self-Concept Scale. Results were analyzed both statistically from objective scoring systems, and clinically from direct observations and from an analysis of the interaction of abused children with the examiner. The results show that while the mental representations did not statistically differ between the sexually and physically abused children, the abused groups did differ in their internal images compared to nonabused but distressed children. Also, abused children tended to split off from consciousness the more negative aspects of their perceptions. The results demonstrate that it is abuse per se, and not simply family distress, that results in impaired object relations. Implications of these results are discussed.

Child↗

Improvement in psychological functioning among drug abusers: inpatient treatment compared to outpatient methadone maintenance.

A total of 68 opiate and cocaine abusers, receiving hospital-based, multimodal treatment for drug abuse in a 14 to 21-day program, and 47 patients newly admitted to methadone maintenance were compared on changes in psychological functioning, using a pretreatment-posttreatment design. Psychological changes were assessed by the Adjective Checklist, measuring the construct of "need". Inpatient treatment resulting in abstinence was associated with positive, meaningful, and significant changes in need pattern that were internally consistent. An equivalent amount of time on methadone maintenance outpatient treatment produced no improvement in psychological functioning, except that these patients evidenced increased dependency needs. Implications are discussed.

Adaptation, Psychological↗

MMPI characteristics of drug abusers with and without histories of suicide attempts.

Compared to drug addicts without histories of suicidal attempt (n = 50), drug addicts who have attempted suicide (n = 50) were characterized by higher levels of maladjustment--particularly in the areas of depression, feelings of alienation, and use of projection and externalization--and were more emotionally withdrawn. Certain Minnesota Multiphasic Personality Inventory (MMPI) codetypes appeared in the attempt group that were not present in the no history group. Drug addicts with suicidal ideation but no history of attempt (n = 13) were not significantly different from the other two groups, and their inclusion as a comparison group masked the real differences between the other two groups. The MMPI results suggest it may be possible to identify a suicide attempt group in substance abusers but not when contrasted with a suicidal ideation group. Treatment implications are considered.

Adult↗