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Biomedical subjects

R Vejlsgaard

Publications and source records attributed to R Vejlsgaard.

At least 55 records · Page 3Linked to original sources
PubMed1980

Netilmicin in urinary tract infections.

30 urological patients with normal renal function were treated with netilmicin because of urinary tract infections, mostly recurrent and due to predisposing factors. the drug was given in doses of 4 mg/kg/day for 4-9 days. All but 5 patients had resolution of their signs and symptoms, and the bacteria were eliminated in 23 patients, with recurrence in 8 and reinfection in 3. The bacteria persisted in 1 patient and the results were indeterminate in 6 patients. No signs of hematopoietic, renal and hepatic toxicity occurred, and vestibular and auditory functions were undisturbed. Regular assays of serum drug concentrations revealed no signs of accumulation. Netilmicin given in doses of 4 mg/kg/day is an efficient antibiotic with low toxicity in the treatment of urinary tract infections.

Adolescent↗
PubMed1980

Multipractice studies: significance of the information given to participating doctors.

A total of 1,176 general practitioners were asked to take part in a multipractice study. One group of 568 practitioners was given very detailed information about the study and 19.7 per cent agreed to take part. The remaining 605 practitioners were given only a brief introduction to the study. Of this group 33.4 per cent agreed to take part. Two thirds of the doctors participating in the trial were sent weekly reminders about the study while the remaining third were not. We found that the reminders did not affect the number of patients registered by the practitioners.

Data Collection↗
PubMed1980

Multipractice studies: how representative are the participating doctors?

General practitioners participating in a multipractice study were compared with those who refused to participate. We found that younger doctors, doctors in partnerships, and doctors with many patients were represented more among participants. However, no correlation was found between the number of patients examined for urinary tract infection in connection with the study.

Data Collection↗
PubMed1979

Treatment of urinary tract infections with sulphonamide and/or trimethoprim. A preliminary report from a multipractice study.

In a double-blind study 1194 patients with bacteriologically diagnosed urinary tract infection were randomly selected for treatment with either 1 g sulphamethizole twice daily, 200 mg trimethoprim twice daily, or 410 mg sulphadiazine plus 90 mg trimethoprim twice daily. All drugs were administered perorally for seven days. Two weeks after commencement of therapy 70% of the patients treated with sulphamethizole, 80% of those treated with trimethoprim and 85% of those treated with sulphadiazine/trimethoprim had sterile urine. After ten weeks 25% of the patients had bacteriuria irrespective of the form of treatment. Side-effects such as skin reactions occurred in 4.1% of the patients treated with trimethoprim alone, in 1.4% of those treated with sulphamethizole and in 3.2% of those treated with trimethoprim/sulphadiazine.

Adolescent↗
PubMed1978

The influence of wound drainage on the infection rate in kidney transplant patients.

The frequency of wound infection was studied in 92 patients who had received cadaver kidneys. Wound drainage was performed in 26 patients and not performed in 66 patients. Wound infection was found in 31% of the wounds with drainage and in 14% of wounds without primary drainage. The results were compared with the frequency of 34% infected wounds in a previous report where wound drainage was performed routinely. It is advised that, when possible, wound drainage should be avoided.

Drainage↗
PubMed1978

Diagnostic catheterization and bacteriuria in women with urinary incontinence.

The risk of single catheterisation in females with urinary incontinence and/or genital prolapse was studied in patients referred for urodynamic examination. Two hundred and eighty-six catheterisations were performed followed by a mid-streem specimen 1 week later, and in 31 of these the initial specimen contained more than 10(5) bacteria. Following catheterisation bacteriuria occurred in 5 (2%) of the patients with initially sterile urine. The phenomenon of "asymptomatic bacteriuria", "transient significant bacteriuria" and "bladder defence mechanism" is discussed. The risk of introducing urinary tract infection in urodynamic studies is low.

Adult↗
PubMed1977

Detrusor hyperreflexia and bacteriuria.

In a retrospective study of 579 patients with cystometrically proven detrusor hyperreflexia bacteriuria was correlated to the commonly accepted etiologies, and to the duration and amplitude of the uninhibited bladder contractions. Blood flow in the bladder wall may be reduced by increased intravesical pressure due to detrusor hyperreflexia, and it has been suggested that a resulting weakening of antibacterial defense mechanisms is responsible for the majority of urinary tract infections in these patients. We have not been able to confirm this hypothesis. We found no statistically significant difference between the incidence of bacteriuria in patients with low amplitude and short duration of the bladder contractions and in patients with high amplitude and long duration of the uninhibited bladder contractions.

Bacteriuria↗