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Biomedical subjects

S Abrams

Publications and source records attributed to S Abrams.

At least 73 records · Page 4Linked to original sources

Phase II study of divided-dose vinblastine in non-small cell bronchogenic carcinoma.

A role for vinblastine (VBL) in lung cancer has never been clearly defined. Because of recent pharmacokinetic data suggesting a biweekly schedule for VBL and recent antitumor activity shown for vindesine, a phase II trial of divided-dose VBL was initiated. Among 22 evaluable patients, a 27% major response rate was seen, with a median duration of 5.5 months (range 3.5-12+). The major toxic effect was myelosuppression but was easily manageable and tolerated. These results suggest schedule dependency for VBL and open the question of its efficacy in lung cancer.

Aged↗

Therapeutic action and ways of knowing.

I have tried to do three things: To propose a working hypothesis to conceptualize the action of the psychoanalytic process in children; in the hypothesis such action is linked to changes in ways of knowing; to offer the beginning of an outline of the steps in the developmental sequences of knowing in childhood; and to demonstrate the applicability of the working-hypothesis and the sequence in development by way of a clinical case illustration.

Child↗

The teaching and learning of psychoanalytic developmental psychology.

I have described three areas in psychoanalytic education where I believe greater attention to existing methods is necessary so as to facilitate the learning of certain principles of development. Explanations might be enhanced by including constructivist with reductionist elements; metapsychology might be clarified in a way that would make the "developmental" more available to analytic scaffolding; and finally, the technical precepts that help focus on the emergence of regressive trends should be broadened to permit enhanced awareness of the progressive trends as well.

Adolescent↗

The genetic point of view: antecedents and transformations.

It seems educationally advantageous to focus renewed attention on the different sets of propositions encompassed within the genetic point of view. Those assumptions fall into two major classes: antecedents and transformations. Custom and usefulness seems to have brought these two together in the present classification of metapsychology. This re-emphasis of the differences between them appears warranted to further assert their distinctions and enhance the applicability of both.

Genetics, Behavioral↗

Object orientedness: the person or the thing.

Infant observation indicated that there is an individual variation in development characterized by orientedness either toward the animate or toward the inanimate world. These variants, which are manifest as early as the second month of life, influence the surrounds, the continuing developmental processes, and certain aspects of character formation. Each variation in orientedness evokes a preferred way of processing percepts and situations.

Child↗