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Biomedical subjects

S Dash

Publications and source records attributed to S Dash.

At least 109 records · Page 6Linked to original sources
PubMed1986

Monoclonal gammopathy in beta thalassaemia.

A rare instance of IgG-kappa monoclonal gammopathy in a patient with beta-thalassaemia trait is reported. The patient had a smoldering multiple myeloma with no apparent clinical symptoms pertaining to the disease and was a non-responder to conventional Melphalan and prednisolone therapy. Beta-thalassaemia trait was detected while investigating him for anaemia. A state of altered immunological reactivity, chronic infections and associated biliary tract disease are some of the pathogenetic mechanisms suggested. However in this patient none of these were operative.

Humans↗
PubMed1980

Spectrum of haemolytic anaemias in Punjab, North India.

Between July 1974 and June 1978 the diagnosis of haemolytic anaemia was made in 267 patients. Thalassaemia major was the leading cause (40-50%) every year except in 1977, when a sharp rise in drug induced haemolysis in G-6-PD deficient patients (61.3%) was encountered. This was possible due to an increase in incidence of vivax malaria and the use of anti-malarial drugs in that year. Abnormal haemoglobins were noted in 9.7% of the total number of patients. Hereditary spherocytosis, autoimmune haemolytic anaemias and paroxysmal nocturnal haemoglobinuria formed a minor cause. Others included copper sulphate poisoning, snake bite, hornet sting and Plasmodium falciparum infection.

Adolescent↗
PubMed1980

Spinal cord compression in homozygous beta thalassaemia.

Spinal cord compression due to extramedullary haemopoietic tissue in a case of beta thalassaemia and G6 PD deficiency is described. Surgical decompression alone had no beneficial effect. However, the addition of radiotherapy proved very useful.

Adult↗