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Biomedical subjects

S Perry

Publications and source records attributed to S Perry.

At least 199 records · Page 11Linked to original sources
PubMed1981

Adaptation of residents to consultation-liaison psychiatry. I. Working with the physically ill.

When working with hospitalized physically ill patients, psychiatry residents may impose a pseudoanalytic, rigidly biological, or overly sympathetic approach. These approaches often fail to address the special requirements and altered psychological state of the physically ill. To have a therapeutic impact on such patients, the psychiatrist needs to assume an engaging, more spontaneous "therapeutic stance" and deviate from anonymity, abstinence, and neutrality. In learning how these deviations are dictated by the therapeutic intent by the patient's character style and psychodynamics, the resident acquires a model of influence useful in other areas of psychiatry.

Adaptation, Psychological↗
PubMed1981

Adaptation of residents to consultation-liaison psychiatry. II. Working with the nonpsychiatric staff.

When working with the staff in a general hospital, psychiatry residents may be overly competitive, solicitous, or detached. These defensive reactions often arise because of the special challenges of performing a consultation, including the skepticism about the value of psychiatry and the demeaning or unrealistic expectations about what the psychiatrist can do. Furthermore, the psychiatry resident feels even more challenged if the attitudes and behavior of the staff must be changed for the patient's benefit. To affect this influence on the staff the psychiatry resident may need to assume a "liaison stance." This stance involves not only establishing a collegial alliance but also using modified therapeutic maneuvers to alter staff behavior. By applying psychodynamic knowledge to understand and potentially to influence the staff, psychiatry residents, as participant observers, can feel less helpless and frustrated by difficult liaison situations.

Adaptation, Psychological↗
PubMed1980

Long-limbed campomelic dwarfism. A radiologic and pathologic study.

Comparison of the roentgenographic and pathologic features of a case of classic, long-limbed campomelic dwarfism with those of previously reported cases leads to the conclusion that the bony abnormalities in this disorder are not due to an intrinsic abnormality of cartilage formation or of osteoblast or osteoclast function. Likewise, no defect in bone collagen, ground substance, or mineralization is evident. The bowing of the long bones may be the result of poorly understood muscular stresses operative in utero. Widespread defects in other organ systems are present, with considerable variation from patient to patient. Phenotypic females with disorder commonly suffer from gonadal dysgenesis. Autosomal recessive inheritance is suggested for a subgroup of these patients, but environmental factors may be causative in some instances.

Abnormalities, Multiple↗
PubMed1980

The applicability of freeze-thaw Percoll gradients to whole-cell isopycnic fractionations: preliminary results.

The freeze-thaw method of gradient generation, using Percoll as the density medium, is shown to be adaptable for the isopycnic sedimentation of live whole cells. Methods of controlling gradient profiles are examined with preliminary evidence showing that three types of cells brought to isopycnic equilibrium in these gradients and recovered from them retain satisfactory levels of several vital functions.

Animals↗
PubMed1979

NIH panels analyze issues on technology.

Experts at NIH's "consensus development" technology assessment conferences study a wide range of issues and make recommendations to help guide users of medical technologies.

Congresses as Topic↗
PubMed1978

Quantitative description of cell cycle kinetics under chemotherapy utilizing flow cytometry.

A discrete time cell cycle kinetics model is developed to account for the effects of cytotoxic chemotherapy, particularly including the existence of cells destined to die. A model structure is determined from related experiments, leaving key parameter values undetermined. These values are found by determining the best least squares fit of the predicted to the observed DNA distribution data at a series of time intervals. The numerical methods include separable least squares, linear inequality constrained least squares and the Gauss--Newton method. This approach is applied to an experiment in which the Ehrlich ascites tumour was given a single dose of bleomycin. The results include several different parameters, including the age response function and a time series of cell age and DNA distributions, which can be used as a basis for further treatment.

Animals↗