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Biomedical subjects

S Tanchev

Publications and source records attributed to S Tanchev.

At least 37 records · Page 2Linked to original sources
PubMed1997

[The plasma concentrations of thiocyanates, estradiol (E2), follicle-stimulating hormone (FSH) and prolactin (Prl) in women smokers].

By the help of biochemical methods we examined the plasma concentrations of thiocyanate during the placental period of the delivery both in mothers and the umbilical vein of the newborn babies. Using radiological methods we simultaneously examined the levels of E2, FSH, and Prl. The results suggest high correlation, between the plasma levels of thiocyanate both and newborn babies. We observed a low positive correlation, conserving the concentration of thiocyanates in mothers and E2 and Prl. There was a negative correlation, concerning the plasma FSH. We also observed similar interrelations in the blood examinations of the umbilical vein of the newborns. To define the level of intoxication of women smokers during gestation it is recommended to define plasma concentration of thiocyanates which influence specifically the production of E2, FSH, and Prl.

Estradiol↗
PubMed1996

[The clinical picture of the fetal alcohol syndrome].

Six new cases of alcoholic embryopathy on newborn children are described. We found out that the mother suffers from chronicle alcoholism. The diagnosis fetal alcohol syndrome is made because there are the minimal diagnostically syndromes: prenatalis hypotrophia, microcephalia, mental retardation, face dysmorphism, cardinal anomalies. We have observed an unfolded clinical picture with added hypertrophia on the clitoris and anomalies of the kidneys on one of the children. With the description of the cases we direct obstetrician's and neonatologist's attention to this current in this moment medical problem.

Female↗
PubMed1996

[The testicular feminization syndrome combined with disseminated hemangiomatosis].

It is described a new born child with many hemangiomas on the liver. It is made a karyogram to exclude. The possibility of chromosome disease. We fixed male karyotype 46 XY--syndrome Morris. We found out that it is a rare combination of testicular feminization with disseminated hemangiomatosis. After the medical treatment with high doses of cortisone the hemangiomas decreased their sizes.

Androgen-Insensitivity Syndrome↗
PubMed1995

[Risk factors for premature rupture of the amniotic sac and neonatal sepsis].

The aim of the study is to assess risk factors, who act directly or indirectly and mechanisms for PROM and neonatal sepsis. There has been examined 74 pregnant women and their newborn 38 infants was with proved neonatal sepsis. There has been established combination from factors for PROM (mechanical--88.4%, infectious--77.8%, and other factors--63.4%).

Adult↗
PubMed1995

[The possibilities for stimulating lactation].

The lactopoesis with Cerucal and by laser acupuncture is stimulated, concerning fifty-four women with an early milk insufficiency. An increase of the quantity of the secreted mother's milk and an increase of the serum level of prolactin have been ascertained. Both methods for stimulating the milk secretion have been recommended. The plan of medical treatment by Cerukal is suitable in an early milk insufficiency of hypoprolactinemic origin. Laser acupuncture is applied successfully in milk insufficiency owning to stagnant and inflammatory changes in the lacteal gland.

Acupuncture Points↗
PubMed1995

[An efficacy and tolerance study of transdermal estrogen replacement therapy with the preparation Systen R50 (Cilag)].

Results from the first study, carried out in our country on the therapeutic effects of Systen [correction of System] R50 TTS in women with peri- and postmenopausal symptoms are reported. Eight women with postcastration syndrome and seven women older than 50 years, with an intact uterus and no vaginal symptoms are reported. Eight women with postcastration syndrome and seven women older than 50 years, with an intact uterus and no vaginal bleeding for at least 6 months were treated. Progesterone was prescribed in the non-hysterectomised patients. In all women enrolled in the study the application of the preparation Systen [correction of System] R50 TTS led to a significant improvement of peri- and postmenopausal symptoms without serious side effects.

Estradiol↗
PubMed1995

[Pregnancy and labor in 335 cases of high multiparity].

It had been accomplished an investigation upon the pregnancy and the birth of 335 women in labour with high (> or = 5) parity (grandmultimaras = GM), including 11 736 labour, taking place in the Clinic of Obstetrics of Pleven Medical University. Controllable group had been formed out of a 655 women in labour with a parity from 1 to 4. It had been used a questionnaire method. Higher in the main group was the frequency of a hypertension, placental pathology (pl. praevia, abruptio et retention placentae) and that of a transverse and oblique presentation of the foetus. Lower in GM was the frequency of the neonates with a very low birth weight < 1500 g (VLBW), the frequency of induction and stimulation of the labour act, and of episiotomy and ruptures of the perineum. We come to the conclusion about the low level of obstetric risk with GM when there was an accessible and a competent obstetric assistance.

Adult↗
PubMed1995

[Serum levels of prolactin, progesterone and estradiol in nursing mothers].

The serum concentrations of prolactin, progesteron and estradiol affecting twenty-four parturients in the puerperium period are studied. The proportion of prolactin on one hand in accordance with progesteron on the other hand are examined. The required condition for lactogenesis is serum concentration of prolactin above 100 ng/ml and the low levels of progesteron and estradiol. The effect of primary breast feeding on the level of prolactin concerning ninety suckling mothers has been studied. The installment of a breast six hours after child-bearing stimulates the prolactin synthesis whereas the late breast feeding after seventy-two hours decreases the concentration of prolactin and suppresses lactation.

Breast Feeding↗
PubMed1994

[Contraception among adolescents].

Adolescence is a period of which the contraception is difficult, because of lower compliance of the teenagers to this methods. The authors were observed the contraceptive uses in 792 pregnant adolescent girls, 264 of which with abortions (group A) and 528 teen-age mothers (group B). Only 12.88% of all patients have used birth control methods, usually with low and middle effects. We founded only 15 patients (1.89%) practiced hormonal contraception and 1 case (0.13%) with Intrauterine devise. The condoms for men was the most popular and useful in teenagers (4.23%), and Natural family planning methods were practiced from 52 (6.57%) patients. There was the statistically differences between adolescent girls included in group A and B about their contraceptive behaviors and live standards (p < 0.01). By the kind of contraceptive methods, there was a high differences in the teenagers with a hormonal uses (p < 0.05).

Adolescent↗
PubMed1993

[Doppler velocimetry of the fetal and the uterine-placental blood flows in pre-eclampsia and fetal retardation].

The aim of the authors is to point out the value of the Doppler velocimetry in the prediction of perinatal distress and the place of Doppler investigation in the management of high risk fetus. In 17 pre-eclamptic and 20 normotensive pregnant women, the blood flow velocity in the uterine and umbilical artery was investigated. It was proved that the changes in the blood flow velocity are feature of some placental disturbances that lead to fetal retardation. The place of that method is controversial for active obstetric management.

Blood Flow Velocity↗
PubMed1993

[Primiparae--the role of age on the duration and disorders in the progression of labor].

The authors have made a study of age influence on the delivery duration and the breaches of delivery progress by women giving birth for the first time. In 6 groups 742 first birth giving women are investigated. The authors have found out a correlation between the age growth, particularly after 25 years, and the total delivery duration increase. Using the Friedman's partogram, the delivery activity have been analyzed. Significance of delivery progress breaches are found out mostly during the active phase-protracted active phase and secondary protracted active phase. There wasn't found out correlations between the age and growth and the latent phase protraction, and the arrest disorders.

Adolescent↗
PubMed1993

[Hysterectomy in obstetrical practice (1979-1990)].

Caesarean hysterectomy and hysterectomy after vaginal delivery from 1979 to 1990, the indications, the complications and the mother's outcome are retrospective investigated. By 41010 births the hysterectomy rate is 0.068%, caesarean hysterectomy-15 (0.056%), and hysterectomy after vaginal delivery-12 (0.030%). The common est caesarean hysterectomy indications are infected uterus, haemorrhage, myoma, carcinoma colli uteri (80%). Haemorrhage and rupture uteri (75%) are the general hysterectomy indications after vaginal birth. A low complication rate is found out, 3 women are deceased (11.11%) in the group of hysterectomy after vaginal delivery. The authors have underlined benefits of the preferred recently organ keeping approach.

Bulgaria↗
PubMed1992

[The "splenic emergency syndrome" during pregnancy (a report of 2 cases)].

The syndrome "urgency of lienal origin" during a pregnancy consists of two syndromes--violent spontaneous pain in the left hypochondrium or in the epigastrium, shortly followed by haemorrhagic shock. Occasionally some other symptoms are present--nausea, vomiting, powerless prolonged labor, innervation of the phrenic nerve. The cases of spontaneous spleen rupture as well as ruptures of splenic vein or artery also assessing to this syndrome. Mean maternal mortality is over 70%. The authors present two cases: the first one--a case of spontaneously ruptured splenic artery aneurysm, the second one--of splenic rupture. The first of two cases came of successful for both mother and baby. This is the sixth similar case described in literature till 1978. The second case presented--a spontaneous lienal rupture, is very rare. The favourable prognosis is entirely determined by prompt diagnosis.

Adult↗
PubMed1992

[The effect of E2 and progesterone on the receptor status in endometrial carcinoma].

The authors study the plasma levels of E2 and progesterone in 62 women with EC. Parallelly the ER and PR in the same number of cases have been studied. The values of E2 in the plasma of ER+ are much lower than those of E2 in ER-. The quantity of E2 and progesterone influence the values of ER and PR in cancers of women in pre and postmenopausal age. In positive ER and PR patients the level of E2 and progesterone is lower in comparison of ER- and PR-.

Carcinoma↗
PubMed1990

[Surgical contraception after cesarean section].

Cesarean section is a routine operation in the obstetric practice and is performed by medical indications only taking into consideration life and functional integrity both of the mother and the fetus. Our studies show that operative contraception together with cesarean section is made in 92% of parturients over 30 years of age in accordance with the required practice. The physician proposes in 16% of women, but in the remaining parturients as in all cases the the consent is documented by the signature of the parturient. Death of children (it is assumed that 2 children are indication for sterilization) due to various causes and operative deprivation of the woman from her child-bearing capability raises moral, ethic and legal questions. On the first place-indications for sterilization during cesarean section. How such type of operation should be made either by the initiation of the physician or after premeditated desire of the parturient. Is it sufficient her consent orally or written. Is the consent of the husband needed and under what form, since he could raise the question about punishment of the physician-obstetrician. The question about danger of healthy and life is not on the last place as well. Our studies during the last 5 years show that this type of intervention is frequent phenomenon--16.34% of the undergone operative deliveries. Furthermore this type of intervention should be performed only by medical indications, having in mind their significance for the future mother, family and society.

Bulgaria↗