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Biomedical subjects

V Cerný

Publications and source records attributed to V Cerný.

At least 55 records · Page 3Linked to original sources
PubMed1986

Arbovirological survey in Silica plateau area, Roznava District, Czechoslovakia.

The serosurveys conducted in the Silica plateau area of the Slovak karst region revealed the presence of specific neutralizing antibody against tick-borne encephalitis (TBE) virus in 18% of local inhabitants (33 examined, mostly goats and sheep farmers), 54% of goats (26 examined), 18% of sheep (120 examined) and 13% of cattle (60 examined), against Lipovník (LIP) virus in 30% of inhabitants, 88% of goats, 55% of sheep and 45% of cattle, and against Bhanja (BHA) virus in 27% of inhabitants, 46% of goats, 29% of sheep and 23% of cattle. The results of hemagglutination-inhibition tests with TBE and BHA antigens were analogous. A detailed analysis of these serologic data points to a recent enhancement of the circulation of LIP and BHA viruses and to a very low TBE virus activity in this natural focus of arboviral infections. The immunological surveys of the 32 former "Roznava disease" patients, conducted 25 years after an extensive epidemic of a TBE virus infection that originated in Roznava in 1951, revealed the presence of neutralizing (and also hemagglutination-inhibiting) antibodies against TBE virus in as many as 78% of cases. Antibodies against LIP and BHA viruses were also detectable in the sera of 16% and 9%, respectively, of these individuals. Populations of the ectoparasites examined for the presence of arbovirus comprised 231 Ixodes ricinus, 806 Dermacentor marginatus and 204 Haemaphysalis punctata ticks and 117 specimens of the louse-flies Melophagus ovinus. Two strains of arbivirus that were antigenically related to Lipovník and Tribec viruses belonging to a group of Kemerovo viruses were isolated from male and female I. ricinus ticks collected from cattle.

Adolescent↗
PubMed1986

Some features of the ecology of fleas inhabiting the nests of the suslik (Citellus citellus (L.)). I: Population dynamics, sex ratio, feeding, reproduction.

While studying the suslik fleas in artificial nests planted in free nature, significant changes in the population dynamics of N. setosa, C. simplex and C. orientalis (from the spring build up to the autumnal peak and the decrease of flea number until the next spring) were noted. The predominance of females in the spring period was recorded in N. setosa. Significant seasonal changes in the number of engorged females of N. setosa and C. simplex and of C. orientalis males (the increase of engorged specimens in the spring and summer) were demonstrated. A significant predominance of females with mature eggs in the spring and summer and their negligible number in the autumn were found in N. setosa and C. simplex.

Animals↗
PubMed1986

A contribution to the methods of estimating absolute tick numbers.

The method of estimating tick numbers in nature by means of experimental sites and by subsequent determination and comparison of classes of occurrence frequency, originally developed for estimation of the numbers of adult Ixodes persulcatus in the Far East and Udmurtia, was successfully applied to imagoes and nymphs of Ixodes ricinus occurring in typical Central European biotopes.

Animals↗
PubMed1984

Occurrence of ixodid ticks--the main vectors of tick-borne encephalitis virus in urbanized territory.

The influence of urbanization on ticks I. ricinus and I. persulcatus--the main vectors of tick-borne encephalitis virus is discussed on the basis of concrete examples. It has been revealed that under favourable conditions the populations of these tick species can exist for a long time not only in towns and new housing estates, but in the old residential districts as well. The necessity of studying the ecology of urban populations of ixodid ticks is pointed out.

Animals↗
PubMed1982

Possible role of birds and ticks in the dissemination of Bhanja virus.

Several wild birds (4 Fringilla coelebs, 1 Coccothraustes coccothraustes and 2 Erithacus rubecula) were inoculated subcutaneously with Bhanja virus (BHAV). No clinical symptoms of infection were observed in any of the birds; a low viremia was demonstrated only in C. coccothraustes (2 and 4 days p.i.), seroconversion in all birds. BHAV was not isolated from organs 32 days p.i. Consequently, the tested birds do not seem to serve as "amplifying hosts" of BHAV. The paper includes a survey of geographic distribution of Bhanja virus and a list of its vectors. A hypothesis on the indirect dissemination of BHAV by birds by means of infected ticks is discussed. According to this hypothesis the European birds could be divided into 3 categories: 1. birds of the Palaearctic-African migration system in which African vectors of BHAV were detected and which could introduce into southern parts of the Palaearctic Region infected ticks from tropical savannahs of Africa (i.e., the biome of main BHAV distribution), 2. migratory birds, hosts of BHAV vectors occurring in southern Europe, which could transfer viruliferous ticks from South to Central Europe, 3. sedentary or migratory birds of steppe or forest--steppe biotopes, hosts of BHAV vectors, which could increase the virus circulation in natural foci either by dispersion of infected ticks to short distances or by a support of their life cycles.

Animals↗
PubMed1981

Treatment of adult acute lymphoblastic leukemia: results of two trials.

Thirty eight patients with acute lymphoblastic leukemia were treated protocol 0171 (VCR, PRED, MTX, cyclophosphamide +/- +/- 6-MP) and protocol 0276/A (VRC, PRED, L-ASP, MTX, 6-MP, cyclophosphamide). Overall complete remission rate in both studies was 84--85%, and additional treatment in protocol 0171 resulted in complete remission rate of 92%. Median duration of complete remission in protocol 0171 was 23 months and median survival of all patients was 33 months. Six patients randomized to regimen "A" (without 6-MP in intensification) had median duration of complete remission 8 months and media survival was 13 months. Seventeen patients treated with regimen "B" (with 6-MP in intensification) had median duration of complete remission 25 months and median survival was 39 months. Median survival of patients allocated on protocol 0276/A in 21+ months and median duration of complete remission is 23 months at present. Twelve percent of patients treated with the best regimen have survived more than 66 months in continuous complete remission. The incidence of drug related death in complete responders was 6%. The relapses were most frequent during the first two years of remission. Extramedullary leukemia as the initial site of relapse was observed in 9% of patients.

Adolescent↗