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Biomedical subjects

V M Sedov

Publications and source records attributed to V M Sedov.

At least 55 records · Page 3Linked to original sources

[Management of infected wounds and trophic ulcers by low frequency ultrasound].

The article is devoted to the investigation of the use of low frequency ultrasound surgical instrument in treatment of trophic ulcers and infected wounds in surgical patients. The method of treatment of these wounds and ulcers by cavitation influence through an intermediate medium was established, an ultrasound surgical apparatus "SUSA-2lf.02", being used, which has been developed and manufactured by AOZT "Medilen"--(St Petersburg). On the base of the experience in treatment of 76 patients intensification of diffusion of the medical preparations into the tissues was shown, among them--into the deep layers of the wound channel. The application of ultrasound provides favourable metabolic changes (normalization of pH of the medium), ensures deep diffusion of medicamentous preparations into the tissues surrounding the ulcers, and enhances therapeutic activity of the preparation.

Adult↗

[Deep multilayer plastic repair in inguinal hernias].

The article presents the authors' variant of a surgical technique of hernioplasty, the so-called deep multi-layer hernioplasty. This type of hernioplasty is thought by the authors to give best results in patients with recurrent and so-called difficult inguinal hernias when there are true anatomic defects of the musculo-aponeurotic and fascial structures. Long-term results of 35 operations were followed-up. Neither recurrences nor complications were noted.

Adult↗

[The efficacy of antithrombotic therapy after total obliteration-reversing therapy in atherosclerotic arterial occlusion of the lower extremities].

The operation of total desobliteration of the arteries (TDA) is a modification of semi-open eversive endarterectomy (EAE). Under study was frequency of thromboses of the desobliteration area, its correlation with postoperative changes of the state of hemorheology and hemocoagulation and the antithrombotic treatment of 150 patients who were operated upon for total desobliteration of the iliofemoral-popliteal segment. The patients were divided into 2 groups which had no substantial difference. At the postoperative period patients of the 1st group (79) were treated with Ticlid ("Sanofi" France) in dosage of 500 mg/day. Treatment of 71 patients of the second group included a combination of two medicines (A + D): aspirin--1000 mg/day and dipiridamol--150 mg/day. A comparative analysis of frequency of the development of cardio-vascular complications at the remote period has shown that in the first group of patients the frequency of development of acute myocardial infarction and acute disturbance of cerebral blood circulation was two times less than in the second group of patients. It is to be noted that in case of the developed in time occlusion in the operation area, the extremity was saved in the Ticlid group in 62% of cases (7 amputations per 18 cases of reocclusion) while in the (A + D) group the extremity was saved in 29% (17 amputations per 24 cases of thrombosis). Thus, the investigation of long-term results of TDA in combination with postoperative antithrombotic therapy of patients with atherosclerotic occlusions of the iliofemoral-popliteal segment arteries has shown high effectiveness of Ticlid. As compared with traditional methods of treatment with aspirin and dipiridamol treatment with Ticlid allowed the cases of restenosis and reocclusions to become more than two times less often.

Arteriosclerosis↗

[Experimental and clinical research on the Russian Vitaflon blood vessel prosthesis].

The authors have performed an experimental and clinical assessment of a new graft. In 37 mongrel dogs 49 experiments were carried out with the implantation of grafts "Vitaflon" into different parts of the arterial and venous bed. It was shown that the domestic graft from modified polytetraftoroethylene had high biological inertia, good plastic properties, zero surgical porosity, strength and reliable "taking" by the recipient's organism. Following the experimental work the prosthesis "Vitaflon" (30-50 cm long and 8 mm diameter) was implanted in the femoro-popliteal-tibial position to 15 patients suffering from obliterating atherosclerosis of the lower extremity arteries. The period of follow-up observations was about 12 months. Thrombosis took place in two grafts in the early postoperative period. Other shunts were functioning well which was confirmed by the clinical picture and dopplerography.

Aged↗

[The prevention of complications in laparoscopic cholecystectomy].

An experience with laparoscopic cholecystectomies in 233 patients is analyzed. The laparoscopic operation is a little invasive method of treatment of cholelithiasis. However intraoperative (5.5%) and postoperative (4.2%) complications are possible. Their risk might be decreased with the following factors taken into consideration: the adequate estimation of indications and contraindications, preoperative preparation of the patients, strict observation of the technology of all steps of the operation, the preparedness of the apparatuses and surgeons. The technical methods are described as well as the measures for prevention of complications after the laparoscopic cholecystectomy.

Adolescent↗

[Laparoscopy in the differential diagnosis and treatment of acute appendicitis and acute gynecological diseases].

Laparoscopy was used in differential diagnostics of acute appendicitis in 524 female patients. Acute gynecological diseases were diagnosed in 123-of them, inflammatory processes in appendages being most frequent. The laparoscopic technology allowed not only to avoid diagnostic errors in all the cases, but also to take all necessary surgical measures. The effectiveness of laparoscopic operations for acute gynecological diseases was confirmed by the absence of complications and recovery within short terms.

Acute Disease↗

[The surgical treatment of aneurysms of the abdominal aorta].

Based on an experience with treatment of 107 patients with aneurysms of the abdominal aorta subjected to planned or urgent operations the authors discuss the problems of the clinical course, diagnosis, indications for operative treatment, the technique of operative interventions and their results. In planned operations lethality was 4.1%, in ruptures of the aneurysm-64.2%. One year after the operations 90% of the patients were practically healthy, 5 years later they were 70%.

Aged↗

[Cardiomyoplasty--a surgical method of treatment in heart failure].

Until recently heart transplantation has been the only method of surgical treatment of severe myocardial heart failure. In the recent years operations of cardiomyoplasty have been performed more and more often for treatment of patients with this disease. The article presents the literature and personal data on the operation technique, indications and contraindications for it. First clinical results of the operative interventions fulfilled since 1994 are discussed.

Adult↗

[Laparoscopic appendectomy in acute appendicitis].

Laparoscopic technology was applied as diagnostic method in 608 patients, 50 patients have undergone laparoscopic appendectomy. There were no diagnostic errors in laparoscopy application. Laparoscopic technology allowed to perform appendectomy quite safely and without any complications. This method permitted considerably reduce terms of treatment of the acute appendicitis patients and quickly restore their ability to work.

Acute Disease↗