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Biomedical subjects

W Woźniak

Publications and source records attributed to W Woźniak.

At least 55 records · Page 3Linked to original sources

[Modern therapy of osteogenic sarcoma in children. Our experience in limb salvage surgery].

The author presents the contemporary multimodality treatment in osteosarcoma in children and adolescents, taking into account salvage surgery and less mutilating surgery. Between 1962 and 1994, 158 osteosarcoma and 105 Ewing's sarcoma patients were treated in The Research Institute of Mother and Child. In these population 60 less mutilating operations were done. The comprehensive therapy influenced positively the results causing the increase of cure rate from 4.5% to 75% in osteosarcoma and from 4.3% to 41.3% in Ewing's sarcoma patients.

Adolescent↗

The spinal accessory nerve in human embryos at 6th week (stages 16 and 17).

Investigations were made on serial sections of human embryos at developmental stages 16 and 17 (37-41 days). The spinal nucleus of the accessory nerve presents well delimited cellular group in the dorsplateral part of the ventral horn of the spinal cord. The migration zone is still present. In embryos of stage 16 the spinal accessory nerve joints the fibers originating from the nucleus ambiguous. This takes place at the level of the inferior ganglion of the vagus nerve. In stage 17 the secondary rami of the accessory nerve develop. This is correlated with the differentiation of the sternocleidomastoid and trapezius muscles.

Accessory Nerve↗

The development of the spinal accessory nerve in human embryos during 5th week (stages 14 and 15).

The spinal part of the accessory nerve was investigated in serially sectioned human embryos at developmental stages 14 and 15. It has been recognized that the spinal accessory nucleus extends through the upper 4 or 6 cervical segments of the spinal cord. The nucleus is formed by group of cells lying dorsolaterally to the primordium of the ventral horn. There is no continuation of the cells forming the spinal nucleus of the XIth nerve with primordium of the nucleus ambiguus. Extramedullary roots of the spinal accessory nucleus form a long trunk ascending into skull and uniting with vagus nerve. In one embryo at stage 15 the spinal accessory nerve separates at the level of the lower ganglion of the vagus.

Accessory Nerve↗

Ensheathing cells in the nerve fiber layer of the olfactory bulb--a novel glial cell type.

Olfactory nerve ensheathing cells (ONECs) were originally described as Schwann cells of the olfactory nerve. More recent studies have suggested that these cells express features of astrocytes, including the lack of basal lamina and collagen fibrils and the failure to ensheath axons individually. Recently performed experimental studies showed that ONECs from the olfactory bulb represent a novel glial cell type.

Animals↗

The number of mitral cells in the adult human olfactory bulb.

The number of mitral cells in layer III and IV was investigated in 8 olfactory bulbs removed from adult humans aged 21, 23, 41, and 42 years. This number was highest in male aged 23 years and in 41 and 43 years old specimens it decreased to the level found in 21 years old female.

Adult↗

Brain-derived neurotrophic factor (BDNF): role in neuronal development and survival.

In 1989 Leitbrock et al. reported the full primary structure of brain-derived neurotrophic factor. The messenger RNA for BDNF was found predominantly in the central nervous system, and the sequence of protein indicated its structural relation to NGF. BDNF belongs to a larger family of neurotrophic molecules. It stimulates the neurite outgrowth and supports neuronal survival.

Animals↗

The vestibulocochlear ganglion in human embryos at stage 13.

In embryos at stage 13th vestibulocochlear ganglion forms a complex structure with the geniculate ganglion. The geniculate ganglion is placed rostrally and may be distinguished from the vestibulocochlear ganglion. Also at this stage there is a sign of differentiation of the vestibular and cochlear ganglia.

Ganglia↗

[Cardiac arrhythmias during extracorporeal shock wave lithotripsy].

Holter monitoring was performed in 55 patients (24 women, 31 men), mean age 50.7 +/- 11.3 who underwent ECG-triggered extracorporeal shock wave lithotripsy (ESWL). Patients were divided into two groups A--30 with history of cardiac disease and B--25 control. The heart rate was significantly higher before and after ESWL in the first group. The number of premature ventricular contractions was higher during ESWL in the same group. No other cardiac complication was observed.

Adult↗