Endodermal sinus tumor is a rare kind of cancer in children. In Clinical Department of Pediatric Oncology there were treated 8 children with endodermal sinus tumor (EST). 4 of them were localised in sacrococcygeal region, 3 in genital system and 1 in testis. In all these cases high level of AFP was observed. Complex therapy was done including surgery, chemotherapy and rtg-therapy, giving as result 3 years survival in 1 only case. Another case is still in course of the treatment. Unified protocol of therapy is not founded till now and prognosis in majority of children is not satisfied.

Antineoplastic Combined Chemotherapy Protocols↗

PubMed1984

[Preliminary elaboration of diagnostic methods for rhabdomyosarcoma in children].

The material basic for this paper consists of 24 children with soft tissue tumors, aged 1-16 years which were diagnosed in the Clinical Department of Child Oncology of the Institute of Mother and Child Warsaw. The diagnostic methods included: interview, physical examination, radiological examination (including CT), bone marrow punction histological investigation by means of fine needle punction and/or biopsy. These methods were sufficient in making a precise diagnosis and staging. The most frequent was stage III (16 cases). It comes from a fact of late diagnosis caused by non characteristic clinical picture. All common localisation was represented in this group (stage III including a cases of causel localisation in the heart.

Abdominal Neoplasms↗

PubMed1984

[Preliminary elaboration of the method of specimen collection using fine-needle biopsy in the diagnosis of rhabdomyosarcoma in children].

Fine needle punction proposed by Martin and Ellis in 1931, is a safe method of diagnosis by means of cytology making possible tumoral verification. In group of 24 children with RMS treated in Clinical Department of Child Oncology, Institute of Mother and Child Warsaw during last 2 years, fine needle punction was made in 7 cases. Precise diagnosis was possible after cytological examination in 2 cases. Non-precise diagnosis confirming malignant tumor only, was done in 3 cases. In resting 2 cases there were no material for evaluation, by means of cytology. Anyhow there was tissue material for histopathological examination. No complications in our material was observed. Fine needle punction is a safe method but requires personal experience of the surgeon and pathologist who performed cytological examination. Method seems to useful in advanced tumors when surgery is limited. Precise diagnosis is possible in short time, and early treatment can be done.

Adolescent↗

PubMed1984

[Preliminary elaboration of the method of complex treatment of rhabdomyosarcoma].

24 children with rhabdomyosarcoma were treated in Clinical Department of Pediatric Oncology of the Institute of Mother and Child, Warsaw during last 2 years. Complex therapy consisted of surgery, chemotherapy, radiotherapy and rehabilitation. Choice method of the treatment depends of stagging by Intergroup RMS Study. Basic method is surgery (radical excision with margin of neighbouring tissue). Modern multi-drug chemotherapy has changed strategy of the treatment by means of less extended surgery. Radiotherapy in RMS has to be mega-voltage what gives short time of irradiation and less complication. Rehabilitation as a component of complex therapy of RMS has to preserve function of treated organ and in cases after mutilated surgery becomes rehabilitated procedure.

Adolescent↗

PubMed1983

The effect of freezing on the sensory properties of Xerocomus badius (Fr, Kühn) and Tricholoma equestre (L ex Fr, Quel).

As the result of sensory and gas chromatographic investigation of the edible mushrooms Xerocomus badius and Tricholoma equestre aroma properties it was stated that freezing preserves the general character of typical aroma. The observed changes were mostly favourable for sensory value intensifying the characteristic for investigated species small and, in the case of T. equestre, lowering the threshold concentration.

Agaricales↗

PubMed1983

Axon diameter and myelin formation in the developing human.

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Axons↗

PubMed1983

Axonal and dendritic growth cones in the developing human spinal cord.

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Axons↗

PubMed1983

[Methods used in the diagnosis and treatment of rhabdomyosarcoma].

The authors present their own clinical material of 74 cases of rhabdomyosarcoma in children, treated in the years 1962-1980. The analysis consists of generally used methods of diagnosis and treatment. Diagnosis was made on the base of clinical, radiological and pathological examination. Treatment was established after stagging qualification and after actually used methods. The treatment based on surgery, radiotherapy, and simple drug chemotherapy was giving bad prognosis and good results was obtained in single cases only. Significant improvement in the results was obtained after multidrug chemotherapy introduced into combined treatment (40%).

Adolescent↗

PubMed1982

Myelination of the human fetal phrenic nerve.

The formation of the myelin sheath of the human phrenic nerve has been studied by electron microscopy in fetuses aged 15, 17, and 23 postovulatory weeks. At 15 weeks, the phrenic nerve is composed mainly of large bundles of axons surrounded by lemmocyte processes. However, fibres at the beginning of myelination are present and show one or one and a half turns of lemmocyte process. At 17 weeks, an increasing number of myelinating fibers can be noted, and the formation of compact myelin and laminated perineurium is detectable. The phrenic nerve presents a mature form by 23 postovulatory weeks. At this time many axons have acquired a thick, compact myelin sheath. However, fibres at early stage of myelin formation are still visible.

Fetus↗