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PubMed · 10609388

Regional myocardial function and microvascular dysfunction. Does the alternate cascade represent ischemia?

J Ross
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ElectrocardiographyHeartHumansMicrocirculationMyocardial IschemiaPrognosisCommentEditorialResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.Review

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J Ross. 1999. Regional myocardial function and microvascular dysfunction. Does the alternate cascade represent ischemia?. https://pubmed.ncbi.nlm.nih.gov/10609388/

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Myocardial infarction in a patient with beta-thalassemia major: first report.

Thalassemia is the most common hereditary anemia throughout the world. Survival in its most severe long-term form, beta-thalassemia major, has significantly risen in the last decades. Cardiac morbidity-heart failure and dysrhythmias-is still the most common cause of mortality in these patients. We describe herein a case of myocardial infarction with normal coronary arteries in a 48-year-old patient with beta-thalassemia and no other recognized risk factors for coronary artery disease. Thromboembolic phenomena, a known situation in these patients, occur at a frequency of 4-5%. However, as far as we know, this is the first report in the literature of myocardial infarction in association with beta-thalassemia. With the notable improvement in the life expectancy of thalassemia patients, ischemic heart disease may become an important complication encountered in these patients.

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