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PubMed · 10795990

Temperature simulations in tissue with a realistic computer generated vessel network.

G M Van Leeuwen·A N Kotte·B W Raaymakers·J J Lagendijk
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Abstract

The practical use of a discrete vessel thermal model for hyperthermia treatment planning requires a number of choices with respect to the unknown part of the patient's vasculature. This work presents a study of the thermal effects of blood flow in a simple tissue geometry with a detailed artificial vessel network. The simulations presented here demonstrate that an incomplete discrete description of the detailed network results in a better prediction of the temperature distribution than is obtained using the conventional bio-heatsink equation. Therefore, efforts to obtain information on the positions of the large vessels in an individual hyperthermia patient will be rewarded with a more accurate prediction of the temperature distribution.

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ArteriesBlood Flow VelocityComputer SimulationHot TemperatureHumansKineticsModels, BiologicalTemperatureVeinsJournal ArticleResearch Support, Non-U.S. Gov't

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G M Van Leeuwen, A N Kotte, B W Raaymakers, J J Lagendijk. 2000. Temperature simulations in tissue with a realistic computer generated vessel network.. https://doi.org/10.1088/0031-9155%2F45%2F4%2F317

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