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PubMed · 10953472

[Oxidative determination of hydroxyamphetamine in drops using flow injection analysis].

J Dolejsová·R Karlícek·M Pospísilová
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Abstract

A flow injection-spectrophotometric determination at 540 nm of hydroxyamphetamine is reported. The procedure is based on a coloured reaction with 2-hydrazono-3-methylbenzothiazole (MBTH) and ceric ammonium nitrate (CeIV) as the oxidation reagent. Under optimised conditions, the determination of hydroxyamphetamine is achieved in a range of 0.01-0.2 mmol.l-1 with a relative standard deviation of 0.78% for 0.05 mmol.l-1 (n = 10) and a sample throughput of 75.h-1. The method was used for the determination of medicinal drug in the mass-produced dosage form of Czech origin: Pedrolon drops, Galena a.c.

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J Dolejsová, R Karlícek, M Pospísilová. 2000. [Oxidative determination of hydroxyamphetamine in drops using flow injection analysis].. https://pubmed.ncbi.nlm.nih.gov/10953472/

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