PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 1127031

Input/output considerations for large data bases.

H Skolnik·J C Synder
View original source ↗Export metadata ↓

Abstract

Input/output devices, format designs, and programming for rejecting defective input, updating and correcting input, and for producing a variety of outputs from the input are discussed, especially from the viewpoint of a large data base and that of the information needs of the users.

Explore related subjects

ComputersElectronic Data ProcessingInformation SystemsPunched-Card SystemsJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

H Skolnik, J C Synder. 1975. Input/output considerations for large data bases.. https://doi.org/10.1021/ci60001a009

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed1992

Molecular orbital study on the glutathione-dependent detoxication of ozonides.

The present paper describes a theoretical study on the mechanism underlying the reaction of cellular glutathione (GSH) with polyunsaturated fatty acid ozonides. The reaction can be catalyzed by glutathione S-transferases and leads to detoxication of the ozonides. Semi-empirical molecular orbital computer calculations suggest that the reaction of glutathione with ozonides involves a nucleophilic attack at one of the carbon atoms of the ozonide ring, instead of at one of the peroxidic oxygen atoms of the ozonide ring. This implies a mechanism different from that of the glutathione S-transferase-mediated reaction with hydroperoxides, previously proposed for the glutathione-dependent detoxication of fatty acid ozonides.

Computers↗