Formats for combinatorial synthesis: solid-phase, liquid-phase and surface.

Nicholas A Boyle; Kim D Janda

doi:10.1016/s1367-5931(02)00308-3

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Formats for combinatorial synthesis: solid-phase, liquid-phase and surface.

Nicholas A Boyle·Kim D Janda

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Abstract

Methods for combinatorial and parallel synthesis continue to evolve in order to meet the demands of modern synthetic organic chemistry. The nature of the support, while typically overlooked, is a key consideration for successful combinatorial organic synthesis. Developments in combinatorial synthesis technologies such as the 'lab-on-a-chip' concept and 96-well-plate-compatible resin plugs have been reported, which should contribute to meeting the increasing challenges of this field.

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Combinatorial Chemistry Techniques Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.Review

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Nicholas A Boyle, Kim D Janda. 2002. Formats for combinatorial synthesis: solid-phase, liquid-phase and surface.. https://doi.org/10.1016/s1367-5931(02)00308-3

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