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[Tryptophan-load in progressive scleroderma (author's transl)].

H W Kreysel·K Meyerhoff·J Kimmig
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Abstract

This presentation describes effects of oral tryptophan loading (5.0 g DL) on tryptophan metabolism in healthy subjects (n = 10) and persons with progressive scleroderma. N1-methylnicotinamide (N1MN), 3-hydroxyanthranilic acid (3 HAA), kynurine (KN), tryptamin (TA), xantheurenic acid (XA) were determinated. Alterations of tryptophan metabolism were evaluated by 24 h urinary excretions of the following metabolites: 5-hydroxy indolacetic acid (5 HAA) and indole-3-acetic acid (IAA). The pathological pathways were discussed, especially the way and influence of serotonine.

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3-Hydroxyanthranilic AcidFemaleHumansHydroxyindoleacetic AcidIndoleacetic AcidsKynurenineMaleNiacinamideScleroderma, SystemicSerotoninSkinTryptaminesTryptophanXanthurenatesEnglish AbstractJournal Article

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H W Kreysel, K Meyerhoff, J Kimmig. 1976-09-15. [Tryptophan-load in progressive scleroderma (author's transl)].. https://doi.org/10.1007/bf01483590

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