Spleen and lymph node reticulofibrosis in "chemically thyroidectomized" rats.

V V Papilian; E Carpen; D Mureşanu; A Olinic; M E Gocan; M Radu-Toader

PubMed · 136602

Spleen and lymph node reticulofibrosis in "chemically thyroidectomized" rats.

V V Papilian·E Carpen·D Mureşanu·A Olinic·M E Gocan·M Radu-Toader

Abstract

The effects of the X-rays on the peripherial lymphoid organs (lymph nodes and spleen) in male adult wistar rats "chemically thyroidectomized" (methylthiouracil) have been studied. Spontaneous death of these animals 9 days after the irradiation was determined by the hypoplasia (aplasia) of the hematogenous bone marrow. The spleen and lymph node changes -- represented by the lymphoid tissue depletion and reticulofibrosis -- in the experimental animals were similar to those observed in animals sacrificed 6-8 months after irradiation. They differed from the latter by the absence of the macromolecular hyperstability of the reticular and collagenous fibers, which is proper to early ageing by X-rays.

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Aging Animals Hypothyroidism Liver Lymph Nodes Male Methylthiouracil Rats Spleen Thyroid Gland Journal Article

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V V Papilian, E Carpen, D Mureşanu, A Olinic, M E Gocan, M Radu-Toader. Spleen and lymph node reticulofibrosis in "chemically thyroidectomized" rats.. https://pubmed.ncbi.nlm.nih.gov/136602/

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