Retention time reproducibility in comprehensive two-dimensional gas chromatography using cryogenic modulation. II. An interlaboratory study.

Robert Shellie; Philip Marriott; Michelle Leus; Jean-Pierre Dufour; Luigi Mondello; Giovanni Dugo; Kefu Sund; Bill Winniford; James Griffith; Jim Luong

doi:10.1016/s0021-9673(03)00938-5

PubMed · 14650621

Retention time reproducibility in comprehensive two-dimensional gas chromatography using cryogenic modulation. II. An interlaboratory study.

Robert Shellie·Philip Marriott·Michelle Leus·Jean-Pierre Dufour·Luigi Mondello·Giovanni Dugo·Kefu Sund·Bill Winniford·James Griffith·Jim Luong

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Abstract

An interlaboratory survey was conducted to determine the reproducibility of retention times in both the first (1D) and second dimension (2D) axes of the two-dimensional separation space, using the longitudinal cryogenic modulation comprehensive two-dimensional gas chromatographic approach. Intralaboratory reproducibility has been demonstrated in part 1 of this investigation [J. Chromatogr. A 968 (2002) 161]. Confidence in absolute retention times (hence component positions) in the two-dimensional separation space is critical to component identification. Comparing data from four independent laboratories, five independent gas chromatographs, five independent LMCS units, and numerous operators has determined that the LMCS cryogenic modulation approach provides reliable comprehensive two-dimensional GC results.

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Robert Shellie, Philip Marriott, Michelle Leus, Jean-Pierre Dufour, Luigi Mondello, Giovanni Dugo, Kefu Sund, Bill Winniford, James Griffith, Jim Luong. 2003-11-26. Retention time reproducibility in comprehensive two-dimensional gas chromatography using cryogenic modulation. II. An interlaboratory study.. https://doi.org/10.1016/s0021-9673(03)00938-5

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