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Talc functionality as lubricant: texture, mean diameter, and specific surface area influence.

J Ribet·K Poret·D Arseguel·D Chulia·F Rodriguez
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Abstract

Talc is widely used as a glidant (flow regulator) for powders. This study highlights the characteristics that confer to talcs new end use properties in improving the lubrication function during compression. We studied the contribution of texture, mean diameter (D50), and specific surface area on the residual die pressure, the ejection pressure, the lubrication index, and the tablet hardness. Different textures were studied: microcrystalline, macrocrystalline, and moderately macrocrystalline talc grade. The compression parameters were improved according to the texture. D50 varies from 0.62 to 15 microm. As D50 decreases, the lubrication performance is improved. Finally, the specific surface area of talcs was studied. This last characteristic of talcs was shown as the most relevant parameter in determining lubrication ability.

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ExcipientsLubricationMaterials TestingParticle SizePowdersPressureTabletsTalcJournal Article

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J Ribet, K Poret, D Arseguel, D Chulia, F Rodriguez. 2003. Talc functionality as lubricant: texture, mean diameter, and specific surface area influence.. https://doi.org/10.1081/ddc-120025870

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