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PubMed · 14677951

Semiconductor quantum dots for photodynamic therapy.

Anna C S Samia·Xiaobo Chen·Clemens Burda
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Abstract

The applicability of semiconductor QDs in photodynamic therapy (PDT) was evaluated by studying the interaction between CdSe QDs with a known silicon phthalocyanine PDT photosensitizer, Pc4. The study revealed that the QDs could be used to sensitize the PDT agent through a fluorescence resonance energy transfer (FRET) mechanism, or interact directly with molecular oxygen via a triplet energy-transfer process (TET). Both mechanisms result in the generation of reactive singlet oxygen species that can be used for PDT cancer therapy.

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Cadmium CompoundsFluorescence Resonance Energy TransferIndolesOxygenPhotochemotherapyPhotosensitizing AgentsQuantum DotsSelenium CompoundsSemiconductorsJournal Article

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Anna C S Samia, Xiaobo Chen, Clemens Burda. 2003-12-24. Semiconductor quantum dots for photodynamic therapy.. https://doi.org/10.1021/ja0386905

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