Making tubes: step by step.

Marta Rosário; Walter Birchmeier

doi:10.1016/j.devcel.2004.06.015

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PubMed · 15239947

Making tubes: step by step.

Marta Rosário·Walter Birchmeier

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Abstract

Branched hollow tubes form the architectural basis of many mammalian organs. The growth factor HGF/SF and its receptor, the Met receptor tyrosine kinase, stimulate epithelial cells to undergo tubulogenesis in vitro. In this issue of Developmental Cell, O'Brien et al. (2004) look at temporal regulation and the role of two HGF/SF effectors, the ERK 1/2 MAP kinases and matrix metalloproteases, in this process.

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Animals Epithelial Cells Hepatocyte Growth Factor Humans Matrix Metalloproteinases Mitogen-Activated Protein Kinases Mitogens Organogenesis Proteins Proto-Oncogene Proteins Proto-Oncogene Proteins c-met Receptors, Growth Factor Viscera Comment Journal Article Review

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Marta Rosário, Walter Birchmeier. 2004. Making tubes: step by step.. https://doi.org/10.1016/j.devcel.2004.06.015

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