PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 1585563

Precautions when using methoxyflurane.

D Dyson
View original source ↗Export metadata ↓

Abstract

Methoxyflurane has a high blood/gas partition coefficient and a low vapor pressure. Mask inductions may be excessively slow, necessitating early high vaporizer control knob settings or additional injectable induction agent. Recoveries may be very prolonged. Methoxyflurane is extensively metabolized, and this may be associated with hepatotoxicity and nephrotoxicity.

Explore related subjects

Anesthesia, InhalationAnimalsDogsHemodynamicsKidneyLiverMethoxyfluraneJournal ArticleReview

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

D Dyson. 1992. Precautions when using methoxyflurane.. https://doi.org/10.1016/s0195-5616(92)50621-0

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed1992

Actions of isoflurane and halothane in pregnant mares.

Eighteen healthy, pregnant mares scheduled for laparotomy and uterine manipulation were randomly allotted to 2 equal groups. After IV administration of xylazine hydrochloride and thiamylal sodium, general anesthesia was maintained with halothane (HALO) or isoflurane (ISO) in oxygen. Results of cardiovascular measurements were similar with both inhalant anesthetics; mean arterial blood pressure was 79 and 82 mm of Hg with HALO and ISO, respectively. Respiratory rate decreased most with ISO (mean frequency was 4 and 9 breaths/min with ISO and HALO, respectively). Partial pressure of arterial CO2 was increased similarly with HALO and ISO. Partial pressure of arterial O2 varied greatly among mares and decreased with duration of use of both anesthetics. Recovery time from anesthesia was significantly (P < 0.05) shorter after use of ISO vs HALO. Minor superficial injuries were associated with recovery from both anesthetics (in 5 mares with ISO and in 1 mare with HALO). Physical signs of postanesthetic myopathy or vital-organ dysfunction were not associated with either agent.

Anesthesia, Inhalation↗
PubMed1992

Postsurgical ventricular tachycardia in a horse.

A 2-year-old Thoroughbred racehorse developed ventricular tachycardia after elective laryngoplasty and ventriculectomy were performed while anesthesia was maintained with halothane. During surgery, the horse became febrile and developed transient mild hypercarbia. The horse was treated with an IV infusion of quinidine gluconate. Continuous electrocardiographic monitoring was used to evaluate cardiac rhythm during treatment, and conversion was achieved after 12 hours of IV infusion. The inciting cause for the arrhythmia was not determined.

Anesthesia, Inhalation↗