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PubMed · 15967537

Hox clusters as models for vertebrate genome evolution.

Simone Hoegg·Axel Meyer
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Abstract

The surprising variation in the number of Hox clusters and the genomic architecture within vertebrate lineages, especially within the ray-finned fish, reflects a history of duplications and subsequent lineage-specific gene loss. Recent research on the evolution of conserved non-coding sequences (CNS) in Hox clusters promises to reveal interesting results for functional and phenotypic diversification.

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AnimalsBase SequenceConserved SequenceDNAEvolution, MolecularFishesGene DuplicationGenes, HomeoboxGenomeHumansModels, GeneticMultigene FamilySequence Homology, Nucleic AcidVertebratesJournal ArticleResearch Support, Non-U.S. Gov'tReview

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Simone Hoegg, Axel Meyer. 2005. Hox clusters as models for vertebrate genome evolution.. https://doi.org/10.1016/j.tig.2005.06.004

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