PubMed · 16463775
[Scanning electron microscopic study of titanium-hydroxyapatite, the functionally graded-material implanted in rabbits].
Abstract
OBJECTIVE: The purpose of this study was to observe the tissue tolerance of Ti-HA functionally graded-material (FGM) and the form of the material-bone interface. METHODS: The sintered Ti -HA FGM, pure HA and pure Ti were respectively implanted into the parietal bone of rabbits. The specimens were observed by SEM at 2, 4, 8 postoperative weeks. RESULTS: In the early stage, the new bone surrounding the Ti -HA FGM formed earlier with larger amount and better maturity than the pure Ti. The condition was similar to the pure HA. Two months after the operation, direct bonding of material-bone interface was formed between the Ti -HA FGM and the new bone as an integral body. However, there was a little space left between the new bone and the pure Ti. CONCLUSIONS: The Ti -HA FGM has good tissue tolerance. Its early integration with bone is similar to pure HA and better than pure Ti.
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Xiao-jun Tang, Shu-zhong Xing, Xiao-ling Song, Lai Gui, Cheng-lin Chu. 2005. [Scanning electron microscopic study of titanium-hydroxyapatite, the functionally graded-material implanted in rabbits].. https://pubmed.ncbi.nlm.nih.gov/16463775/
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