fMRI bold signal analysis using a novel nonparametric statistical method.

Patrick A De Mazière; Marc M Van Hulle

doi:10.1016/j.jmr.2006.12.001

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fMRI bold signal analysis using a novel nonparametric statistical method.

Patrick A De Mazière·Marc M Van Hulle

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Abstract

We present in this article a novel analytical method that enables the application of nonparametric rank-order statistics to fMRI data analysis, since it takes the omnipresent serial correlations (temporal autocorrelations) properly into account. Comparative simulations, using the common General Linear Model and the permutation test, confirm the validity and usefulness of our approach. Our simulations, which are performed with both synthetic and real fMRI data, show that our method requires significantly less computation time than permutation-based methods, while offering the same order of robustness and returning more information about the evoked response when combined with/compared to the results obtained with the common General Lineal Model approach.

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Algorithms Animals Brain Brain Mapping Computer Simulation Data Interpretation, Statistical Evoked Potentials Haplorhini Humans Image Interpretation, Computer-Assisted Magnetic Resonance Imaging Models, Neurological Models, Statistical Journal Article Research Support, Non-U.S. Gov't

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Patrick A De Mazière, Marc M Van Hulle. 2006-12-28. fMRI bold signal analysis using a novel nonparametric statistical method.. https://doi.org/10.1016/j.jmr.2006.12.001

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