Decrease in the number of progenitors of erythrocytes (BFUe, CFUe), granulocytes and macrophages (GM-CFC) in bone marrow of rats after a 14-day flight onboard the Cosmos-2044 Biosatellite.

A Vacek; T V Michurina; L V Serova; D Rotkovská; A Bartonícková

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PubMed · 2070886

Decrease in the number of progenitors of erythrocytes (BFUe, CFUe), granulocytes and macrophages (GM-CFC) in bone marrow of rats after a 14-day flight onboard the Cosmos-2044 Biosatellite.

A Vacek·T V Michurina·L V Serova·D Rotkovská·A Bartonícková

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Abstract

A decrease in the number of progenitors of erythrocytes (BFUe, CFUe) and of granulocytes and macrophages (GM-CFC) in bone marrow was found in rats exposed to microgravitation during a 14-day flight onboard the Cosmos-2044 biosatellite when compared to control rats maintained under conditions of gravitation on the ground. The number of progenitors of both lineages of haemopoiesis was also decreased in synchronous control rats, thus suggesting that the pool of progenitors is influenced also by the action of the nonspecific space flight factors.

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Animals Bone Marrow Cells Cell Count Erythroid Precursor Cells Granulocytes Hematopoiesis Hematopoietic Stem Cells Macrophages Male Rats Rats, Inbred Strains Space Flight Comparative Study Journal Article

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A Vacek, T V Michurina, L V Serova, D Rotkovská, A Bartonícková. 1991. Decrease in the number of progenitors of erythrocytes (BFUe, CFUe), granulocytes and macrophages (GM-CFC) in bone marrow of rats after a 14-day flight onboard the Cosmos-2044 Biosatellite.. https://pubmed.ncbi.nlm.nih.gov/2070886/

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