Cynomolgus monkeys.

D P Rosenberg

doi:10.1126/science.2360042

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PubMed · 2360042

Cynomolgus monkeys.

D P Rosenberg

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Abstract

In the report "Tick anticoagulant peptide (TAP) is a novel inhibitor of blood coagulation factor Xa" by L. Waxman et al. (4 May, p. 593), the second sentence of the caption of figure 2 was printed incorrectly. It should have read, "Determination of the Intrinsic K(i) was done by fitting the observed data (*) with nonlinear regression analysis to the ratio of inhibited velocity (v(i)) to uninhibited velocity (V(o)) described by the equation V(i)/V(o) = [E(t) - I(t) K(*)(i)] + [(I(t) + K(*)(i) - E(t))(2) + 4K(i)E(t)](1/2)/2E(t) derived by Morrison for tight-binding inhibition (7) (solid line), where E(t) and I(t) are the total amount of enzyme and inhibitor, respectively, included in the assay."

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D P Rosenberg. 1990-06-22. Cynomolgus monkeys.. https://doi.org/10.1126/science.2360042

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