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99mTc(Cu)-mannitol complex: a new agent for dynamic renal function studies.

U P Chauhan·J Chander·P Mishra·R C Sarin·R V Narayanan·B Singh
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Abstract

Mannitol has been labeled with 99mTc by using cuprous chloride as a reducing agent. Blood and kidney clearance of 99mTc(Cu)-mannitol was slightly faster than that of 99mTc(Sn)-DPTA in rat and maximum radioactivity ratio of kidneys to blood was 84.6 at 5 min. A comparative study of 99mTc(Cu)-mannitol, 99mTc(Sn)-DTPA was made in rabbits by taking serial images of kidneys and bladder with a gamma camera. Results show superiority of 99mTc(Cu)-mannitol over other agents for dynamic renal function studies.

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AnimalsKidneyMannitolOrganometallic CompoundsOrganotechnetium CompoundsPentetic AcidRabbitsRadioisotope RenographyRatsTechnetiumTechnetium Tc 99m PentetateTissue DistributionUrinary BladderComparative StudyJournal Article

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U P Chauhan, J Chander, P Mishra, R C Sarin, R V Narayanan, B Singh. 1989. 99mTc(Cu)-mannitol complex: a new agent for dynamic renal function studies.. https://doi.org/10.1016/0883-2897(89)90009-3

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