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PubMed · 3209792

Ocular chrysiasis.

D W Tierney
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Abstract

Elemental gold, administered parenterally and orally, is used to a moderate extent to treat rheumatoid arthritis, Sjögren's syndrome and nondisseminated lupus erythematosus. Deposition of gold salts are observable in ocular tissues during chrysotherapy. These tissues are the cornea, conjunctiva, skin, lens and retina. This case report describes ocular chrysiasis and discusses its clinical management.

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Administration, OralAuranofinCorneal DiseasesEyeEye DiseasesFemaleGoldHumansInflammationInfusions, ParenteralMiddle AgedCase ReportsJournal Article

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D W Tierney. 1988. Ocular chrysiasis.. https://pubmed.ncbi.nlm.nih.gov/3209792/

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A randomized crossover study using yohimbine and isoxsuprine versus pentoxifylline in the management of vasculogenic impotence.

PURPOSE: We evaluated the efficacy and safety of yohimbine and isoxsuprine or pentoxifylline in the management of vasculogenic erectile dysfunction. MATERIALS AND METHODS: A total of 20 patients diagnosed with arterial insufficiency and cavernous venous leakage by pharmacological penile duplex scanning underwent nonhormonal oral therapy. A randomized crossover study was performed using 5.4 mg. yohimbine plus 10 mg. isoxsuprine or 400 mg. pentoxifylline 3 times daily. Response to therapy was assessed by a sexual questionnaire and repeat penile duplex ultrasonography. RESULTS: No patient in either phase of the study in either group had a complete response to the oral regimen(s) and there was no improvement in the pre-injection or post-injection cavernous arterial peak systolic flow velocities or resistance indexes. CONCLUSIONS: Our study suggests that these oral agents, although well tolerated, were not effective in the management of these patients with mixed vasculogenic erectile dysfunction.

Administration, Oral↗