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PubMed · 3951917

Necrotizing tracheobronchitis: case report.

F Mimouni·J L Ballard·E T Ballard·R T Cotton
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Abstract

A 33-week-gestation infant with respiratory distress syndrome is reported. At five days of age, acute life-threatening tracheal obstruction occurred, which was relieved after removal of a plug during bronchoscopy. Histologic examination of the plug revealed partially necrotic tracheal mucosa, compatible with the diagnosis of necrotizing tracheobronchitis. At 31 days of age, obstruction recurred due to the development of a tracheal stricture, which resolved after tracheal reintubation (to maintain patency) and corticosteroid therapy. Tracheal stricture may be a long-term complication of necrotizing tracheobronchitis, when the initial episode does not lead to death from obstruction.

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BronchitisCefotaximeDexamethasoneDrug Therapy, CombinationFemaleHumansInfant, NewbornInfant, Premature, DiseasesIntubation, IntratrachealNecrosisRespiratory Distress Syndrome, NewbornTracheitisCase ReportsJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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F Mimouni, J L Ballard, E T Ballard, R T Cotton. 1986. Necrotizing tracheobronchitis: case report.. https://pubmed.ncbi.nlm.nih.gov/3951917/

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Lower respiratory tract infections following cardiac arrest and cardiopulmonary resuscitation.

All episodes of lower respiratory tract infection that developed among 96 patients surviving for > 24 hours after cardiac arrest were prospectively studied over an 18-month period. Pneumonia developed in 23 (24.0%) of patients after a mean of 7 days (SD, +/- 6.2 days). The development of four superinfections raised the cumulative incidence to 28.1%. Purulent tracheobronchitis was diagnosed in three instances. The causative agent of pneumonia was identified in 18 episodes, three of which were polymicrobial. Gram-positive cocci represented 57.1% of isolates, and Staphylococcus aureus--the most frequently isolated microorganism in this population--accounted for two-thirds of all gram-positive cocci. Pseudomonas aeruginosa was isolated in six episodes, five of which were associated with previous antibiotic use. Nine (39.1%) of the 23 patients in the group with pneumonia died, but only one of these deaths was considered to be directly related to pneumonia. In conclusion, pneumonia is a common complication of patients surviving cardiac arrest, but, with adequate treatment, its influence on outcome is marginal. Gram-positive cocci are the predominant pathogens, although infection with P. aeruginosa should be considered among patients receiving antibiotics.

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