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Stability studies on horse antithymocyte globulin.

A J Parcells·H Ko·M E Royer·J N Woody
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Abstract

Two equine antithymocyte globulin preparations were studied with respect to their relative rosette inhibition activity after storage at 4 and 25 C. After storage at 4 C for 48 months no activity loss was observed; 25 C storage resulted in fragmentation and eventual loss of relative rosette inhibition activity. A third preparation was studied by monkey skin graft prolongation. During a 1-year period, there was no loss of immunosuppressive activity as measured by this method and the rosette inhibition assay.

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AnimalsAntilymphocyte SerumCentrifugation, Density GradientDrug StabilityGraft SurvivalHaplorhiniHorsesImmunologic TechniquesImmunosuppressive AgentsMacaca mulattaSkin TransplantationT-LymphocytesTransplantation, AutologousTransplantation, HomologousJournal Article

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A J Parcells, H Ko, M E Royer, J N Woody. 1977. Stability studies on horse antithymocyte globulin.. https://doi.org/10.1097/00007890-197702000-00007

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