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Theta particles: a structure found in hamster sarcoma virus.

A P Albino·E DeHarven·F K Sanders
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Abstract

Hamster sarcoma virus (HaSV), a ribonucleic acid tumor virus, pelleted from tissue culture fluid manifests type C morphology by electron microscopy. However, if virus is first concentrated by polyethylene glycol or ammonium sulfate followed by density gradient banding, the virus shows a dramatically atypical barred core structure, termed "theta particles." This structure suggests a condensation of the ribonucleoprotein into a flat disc. Atypical particles are found with HaSV and not in similarly treated feline leukemia virus or Rauscher-murine leukemia virus. Differences in the composition of HaSV as compared with these other viruses may be responsible for the production of such particles.

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Ammonium SulfateAnimalsCell-Free SystemCentrifugation, Density GradientChemical PrecipitationCricetinaeGlycolsLeukemia Virus, FelineMicropore FiltersMicroscopy, ElectronNucleoproteinsOncogenic VirusesRNA VirusesRauscher VirusSarcoma, ExperimentalStaining and LabelingSucroseVirus CultivationJournal Article

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A P Albino, E DeHarven, F K Sanders. 1972. Theta particles: a structure found in hamster sarcoma virus.. https://doi.org/10.1128/jvi.10.3.477-483.1972

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