A growth factor from spinal cord.

T Jennings; R D Jones; A Lipton

doi:10.1002/jcp.1041000208

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A growth factor from spinal cord.

T Jennings·R D Jones·A Lipton

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Abstract

Mitogenic activity is present at a variety of sites in the central nervous system. A growth factor was purified from neonatal bovine spinal cord. It has a pI of 9.5-9.8 and a molecular weight of about 11,000 daltons. Spinal cord growth factor is a basic polypeptide that is inactivated by extremely acid or basic conditions. Its mobility on SDS polyacrylamide gels suggests that this factor is different from pituitary FGF and brain FGF-1.

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Animals Animals, Newborn Cattle Cell Division Cell Line Electrophoresis, Polyacrylamide Gel Hydrogen-Ion Concentration Isoelectric Focusing Kidney Mice Molecular Weight Nerve Growth Factors Spinal Cord Journal Article Research Support, U.S. Gov't, P.H.S.

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T Jennings, R D Jones, A Lipton. 1979. A growth factor from spinal cord.. https://doi.org/10.1002/jcp.1041000208

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