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PubMed · 490528

Glomerulonephritis associated with polymyositis.

R F Dyck·A Katz·D A Gordon·M Johnson·Z Shainhouse·C J Cardella·R A Bear
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Abstract

Five patients with primary idiopathic polymyositis developed proteinuria associated with urine sediment abnormalities. Renal biopsies disclosed a focal mesangial proliferative glomerulonephritis with deposits of immunoglobulin and complement. After treatment of the polymyositis with corticosteroids, proteinuria and urine sediment changes disappeared within 4 to 8 wk along with an improvement in the muscle disease. Although the pathogenesis remains to be determined, immune complexes may be implicated in the etiology of this renal lesion.

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Adrenal Cortex HormonesAdultAntigen-Antibody ComplexBiopsyFemaleGlomerulonephritisHumansKidneyMaleMyositisProteinuriaJournal Article

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R F Dyck, A Katz, D A Gordon, M Johnson, Z Shainhouse, C J Cardella, R A Bear. Glomerulonephritis associated with polymyositis.. https://pubmed.ncbi.nlm.nih.gov/490528/

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